ArticleFrontiers in medicine2024
Acquired reactive perforating collagenosis triggered by trauma with eosinophilia: a case report and literature review.
Article in Frontiers in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Acquired Reactive Perforating Collagenosis Treated with Upadacitinib: A Case Report and Literature Review.Clinical, cosmetic and investigational dermatology · 2026Article
- Efficacy of Upadacitinib in the Treatment of Acquired Reactive Perforating Collagenosis in a Patient with Type 1 Diabetes: A Case Report and A Literature Review.Clinical, cosmetic and investigational dermatology · 2025Article
- A Case of Acquired Reactive Perforating Dermatosis with Complete Resolution of Eruptions on Upper and Lower Limbs During the Treatment of Diabetes Mellitus and Peripheral Artery Disease.Medicina (Kaunas, Lithuania) · 2024Article
- Development of Pyoderma Gangrenosum in a Patient with Acquired Reactive Perforating Collagenosis.Case reports in dermatologyArticle
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Authors and funding
6 authors.
Funding
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Abstract
Acquired reactive perforating collagenosis (ARPC) is a rare dermatological disorder condition defined by the perforation of altered collagen fibers through the epidermis. The presence of underlying conditions such as diabetes or renal disease is helpful in the ARPC diagnosis. Although skin rashes related to ARPC have been reported, the exact causative factors and mechanisms remain unclear. Here, we present a unique case of ARPC triggered by trauma in a 67-year-old male without concurrent systemic alterations. The diagnosis of ARPC with eosinophilia was made following comprehensive diagnostic testing, including clinical presentation, histological results, and blood tests, ruling out other possible diseases. Intriguingly, the histopathological examination revealed collagen penetration into the epidermis at different tissue sections. In addition, we reviewed existing literature on ARPC, which documented the causation. To help confirm the diagnosis, clinicians have to pay attention to traumatic triggers for ARPC and its rare manifestation with eosinophilia.
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