Evidence map›Paper›PMID 38988171›Full record

SynthesisCurrent pharmaceutical design2024

Chemoprophylaxis Effect of EGCG on the Recurrence of Colorectal Cancer: A Systematic Review and Meta-Analysis.

Benyu He, Shuhui Kang, Runze Su, Sha Wu, Xue Liu, Maosheng Liu, Si Chen

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Current pharmaceutical design, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Benyu HeZunyi Medical University, Zhuhai Campus, Zhuhai, China.
Shuhui KangZunyi Medical University, Zhuhai Campus, Zhuhai, China.
Runze SuZunyi Medical University, Zhuhai Campus, Zhuhai, China.
Sha WuZunyi Medical University, Zhuhai Campus, Zhuhai, China.
Xue LiuSchool of Nursing, Hebei University, Baoding, China.
Maosheng LiuZunyi Medical University, Zhuhai Campus, Zhuhai, China.
Si ChenZunyi Medical University, Zhuhai Campus, Zhuhai, China.

Funding

Guizhou Science and Technology Department (No. Qiankehejichu-ZK [2021] General-414)
6 · The paper itself

Abstract

BACKGROUND AND

aimsThe recurrence rate of Colorectal Cancer (CRC) after cure is always high. The purpose of this study was to investigate whether green tea extract (-)-Epigallocatechin gallate (EGCG) has an effective preventive effect on the recurrence of CRC.

methodsWe conducted a systematic literature review and meta-analysis of the effects of taking EGCG or placebo on disease recurrence in patients after colon polyp removal.

resultsFive Randomized Controlled Trials (RCTs) were included in this review. A double-blind drug trial involving 1389 participants involved EGCG and placebo. The results showed no significant publication bias or heterogeneity in the five studies (I

conclusionThis study demonstrated that long-term EGCG can prevent CRC recurrence to a certain extent.

Indexed as

CatechinColorectal NeoplasmsNeoplasm Recurrence, LocalTeaHumansRandomized Controlled Trials as TopicCatechinepigallocatechin gallateTeachemoprophylaxisColorectal cancerEGCGgreen tea extractmalignant tumour.recrudescence

Identifiers

PMID38988171

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.