Evidence map›Paper›PMID 38988134›Full record

ArticleJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research2024

Following hip fracture, hospital organizational factors associated with prescription of anti-osteoporosis medication on discharge, to address imminent refracture risk: a record-linkage study.

Rita Patel, Andrew Judge, Antony Johansen, Muhammad K Javaid, Xavier L Griffin, Tim Chesser, Jill Griffin, Elsa M R Marques, REDUCE Study Group, Yoav Ben-Shlomo and 1 more

Abstract read
In one paragraph

Article in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Rita PatelMusculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS10 5NB, United Kingdom.ORCID 0000-0002-9136-9529
Andrew JudgeMusculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS10 5NB, United Kingdom.ORCID 0000-0003-3015-0432
Antony JohansenDivision of Population Medicine, School of Medicine, Cardiff University and University Hospital of Wales, Cardiff, CF14 4XN, United Kingdom.
Muhammad K JavaidNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, OX3 7HE, United Kingdom.ORCID 0000-0001-7985-0048
Xavier L GriffinBarts Bone and Joint Health, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, E1 2AT, United Kingdom.ORCID 0000-0003-2976-7523
Tim ChesserDepartment of Trauma and Orthopaedics, Southmead Hospital, North Bristol NHS Trust, Bristol, BS10 5NB, United Kingdom.ORCID 0000-0001-6837-6029
Jill GriffinClinical & Operations Directorate, Royal Osteoporosis Society, Bath, BA2 3BH, United Kingdom.
Elsa M R MarquesMusculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS10 5NB, United Kingdom.ORCID 0000-0003-1360-5677
REDUCE Study Group
Yoav Ben-ShlomoPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS8 2PS, United Kingdom.ORCID 0000-0001-6648-3007
Celia L GregsonMusculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS10 5NB, United Kingdom.ORCID 0000-0001-6414-0529

Funding

National Institute for Health ResearchNIHR Biomedical Research Centre at University Hospitals BristolOxford Biomedical Research CentreUniversity of BristolVersus Arthritis 22086Weston NHS Foundation Trust
6 · The paper itself

Abstract

Patients who sustain a hip fracture are known to be at imminent refracture risk. Their complex multidisciplinary rehabilitation needs to include falls prevention and anti-osteoporosis medication (AOM) to prevent such fractures. This study aimed to determine which hospital-level organizational factors predict prescription of post-hip fracture AOM and refracture risk. A cohort of 178 757 patients aged ≥60 yr who sustained a hip fracture in England and Wales (2016-2019) was examined and followed for 1 yr. Patient-level hospital admission datasets from 172 hospitals, the National Hip Fracture Database, and mortality data were linked to 71 metrics extracted from 18 hospital-level organizational reports. Multilevel models determined organizational factors, independent of patient case-mix, associated with (1) AOM prescription and (2) refracture (by ICD10 coding). Patients were mean (SD) 82.7 (8.6) yr old, 71% female, with 18% admitted from care homes. Overall, 101 735 (57%) were prescribed AOM during admission, while 50 354 (28%) died during 1-yr follow-up, 12 240 (7%) refractured. Twelve organizational factors were associated with AOM prescription, for example, orthogeriatrician-led care compared to traditional care models (odds ratio [OR] 4.65 [95% CI, 2.25-9.59]); AOM was 9% (95% CI, 6%-13%) more likely to be prescribed in hospitals providing routine bone health assessment to all patients. Refracture occurred at median 126 d (IQR 59-234). Eight organizational factors were associated with refracture risk; hospitals providing orthogeriatrician assessment to all patients within 72 h of admission had an 18% (95% CI, 2%-31%) lower refracture risk, weekend physiotherapy provision had an 8% (95% CI, 3%-14%) lower risk, and where occupational therapists attended clinical governance meetings, a 7% (95% CI, 2%-12%) lower risk. Delays initiating post-discharge community rehabilitation were associated with a 15% (95% CI, 3%-29%) greater refracture risk. These novel, national findings highlight the importance of orthogeriatrician, physiotherapist, and occupational therapist involvement in secondary fracture prevention post hip fracture; notably, fracture risk reductions were seen within 12 mo of hip fracture.

Indexed as

Hip FracturesOsteoporosisPatient DischargeAgedAged, 80 and overBone Density Conservation AgentsFemaleHospitalsHumansMaleMiddle AgedRisk FactorsBone Density Conservation Agentsfracture preventionfragility fracturehealth services researchosteoporosisrefracture

Identifiers

PMID38988134
PMCPMC11337946

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.