Evidence map›Paper›PMID 38987696›Full record

ArticleBMC anesthesiology2024

Clinical characteristics of extracorporeal cardiopulmonary resuscitation in China: a multicenter retrospective study.

Zhiyong Yuan, Ying Liu, Guangyao Wei, Fuhua Wang, Bo Yao, Xiaotong Hou, Jinyan Xing

Registry-linked trialAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC anesthesiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04158479 (China Extracorporeal Life Support Registry), which is not on this map. Cited by 2 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04158479 recruitingnot on this map

China Extracorporeal Life Support Registry

Typeobservational_patient_registrySponsorBeijing Anzhen HospitalRan2017 to 2030Enrolled20,000ConditionsCardiogenic Shock, Cardiac Arrest, Heart Failure, Acute Respiratory Distress SyndromeArmsECMO
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhiyong YuanDepartment of Critical Care Medicine, the Affiliated Hospital of Qingdao University, Qingdao, Shandong Province, China.
Ying LiuDepartment of Critical Care Medicine, the Affiliated Hospital of Qingdao University, Qingdao, Shandong Province, China.
Guangyao WeiDepartment of Critical Care Medicine, the Affiliated Hospital of Qingdao University, Qingdao, Shandong Province, China.
Fuhua WangDepartment of Critical Care Medicine, the Affiliated Hospital of Qingdao University, Qingdao, Shandong Province, China.
Bo YaoDepartment of Critical Care Medicine, the Affiliated Hospital of Qingdao University, Qingdao, Shandong Province, China.
Xiaotong Hou *Center for Cardiac Intensive Care, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China. xt.hou@ccmu.edu.cn.
Jinyan Xing *Department of Critical Care Medicine, the Affiliated Hospital of Qingdao University, Qingdao, Shandong Province, China. xingjy@qdu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeExtracorporeal cardiopulmonary resuscitation (ECPR) might markedly increase the survival of selected patients with refractory cardiac arrest. But the application situation and indications remained unclear. MATERIALS AND

methodsWe respectively reviwed all adult patients who underwent ECPR from January 2017 to March 2021. Patient characteristics, initiation and management of ECMO, complications, and outcomes were collected and compared between the survivors and nonsurvivors. LASSO regression was used to screen risk factors. Multivariate logistic regression was performed with several parameters screened by LASSO regression.

resultsData were reported from 42 ECMO centers covering 19 provinces of China. A total of 648 patients were included in the study, including 491 (75.8%) males. There were 11 ECPR centers in 2017, and the number increased to 42 in 2020. The number of patients received ECPR increased from 33 in 2017 to 274 in 2020, and the survival rate increased from 24.2% to 33.6%. Neurological complications, renal replacement therapy, epinephrine dosage after ECMO, recovery of spontaneous circulation before ECMO, lactate clearance and shockable rhythm were risk factors independently associated with outcomes of whole process. Sex, recovery of spontaneous circulation before ECMO, lactate, shockable rhythm and causes of arrest were pre-ECMO risk factors independently affecting outcomes.

conclusionsFrom January 2017 to March 2021, the numbers of ECPR centers and cases in mainland China increased gradually over time, as well as the survival rate. Pre-ECMO risk factors, especially recovery of spontaneous circulation before ECMO, shockable rhythm and lactate, are as important as post-ECMO management,. Neurological complications are vital risk factors after ECMO that deserved close attention.

trial registrationNCT04158479, registered on 2019/11/08. https://clinicaltrials.gov/NCT04158479.

Indexed as

Cardiopulmonary ResuscitationExtracorporeal Membrane OxygenationAdultAgedChinaFemaleHeart ArrestHumansMaleMiddle AgedRetrospective StudiesRisk FactorsSurvival RateCardiac arrestEpinephrineExtracorporeal cardiopulmonary resuscitationExtracorporeal life supportLactic acidNeurological complications

Identifiers

PMID38987696
PMCPMC11234634

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.