Evidence map›Paper›PMID 38987595›Full record

ArticleNature2024

In situ targeted base editing of bacteria in the mouse gut.

Andreas K Brödel, Loïc H Charpenay, Matthieu Galtier, Fabien J Fuche, Rémi Terrasse, Chloé Poquet, Jan Havránek, Simone Pignotti, Antonina Krawczyk, Marion Arraou and 7 more

Abstract read
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed.

  1. Review
  2. Article
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  6. Article
  7. Article
  8. Review
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  10. Review
  11. Article
  12. Review
  13. Research square · 2026
    Article
  14. Review
  15. bioRxiv : the preprint server for biology · 2026
    Article
  16. Article
  17. Article
  18. Review
  19. The gut as a central hub for multi-organ crosstalk in aging.Cellular and molecular life sciences : CMLS · 2026
    Review
  20. Occurrence and applications of CRISPR-Cas systems in bifidobacteria.Applied and environmental microbiology · 2026
    Review

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Andreas K Brödel *Eligo Bioscience, Paris, France.
Loïc H Charpenay *Eligo Bioscience, Paris, France.
Matthieu GaltierEligo Bioscience, Paris, France.
Fabien J FucheEligo Bioscience, Paris, France.
Rémi TerrasseEligo Bioscience, Paris, France.
Chloé PoquetEligo Bioscience, Paris, France.
Jan HavránekEligo Bioscience, Paris, France.ORCID 0009-0008-6227-9517
Simone PignottiEligo Bioscience, Paris, France.ORCID 0009-0003-3660-6960
Antonina KrawczykEligo Bioscience, Paris, France.
Marion ArraouEligo Bioscience, Paris, France.
Gautier PrevotEligo Bioscience, Paris, France.
Dalila SpadoniEligo Bioscience, Paris, France.
Matthew T N YarnallEligo Bioscience, Paris, France.
Edith M HesselEligo Bioscience, Paris, France.
Jesus Fernandez-RodriguezEligo Bioscience, Paris, France. jesus.fernandez@eligo-bioscience.com.ORCID 0000-0003-1618-2841
Xavier DuportetEligo Bioscience, Paris, France. xavier.duportet@eligo-bioscience.com.ORCID 0009-0005-3202-217X
David BikardEligo Bioscience, Paris, France. david.bikard@eligo-bioscience.com.ORCID 0000-0002-5729-1211

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microbiome research is now demonstrating a growing number of bacterial strains and genes that affect our health

Indexed as

CRISPR-Cas SystemsEscherichia coliGastrointestinal MicrobiomeGastrointestinal TractGene EditingAnimalsBacteriophagesbeta-LactamasesFemaleGenes, BacterialGenetic VectorsKlebsiella pneumoniaeMiceTime Factorsbeta-Lactamases

Identifiers

PMID38987595
PMCPMC11338833

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.