Evidence map›Paper›PMID 38987549›Full record

ArticleNature communications2024

Isotopologues of potassium 2,2,2-trifluoroethoxide for applications in positron emission tomography and beyond.

Qunchao Zhao, Sanjay Telu, Susovan Jana, Cheryl L Morse, Victor W Pike

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trifluoromethylation of alkyl electrophiles withScience (New York, N.Y.) · 2025
    Article
  2. [Angewandte Chemie (International ed. in English) · 2025
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Qunchao ZhaoMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, 10 Center Drive, Bethesda, MD, 20892-1003, USA.
Sanjay TeluMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, 10 Center Drive, Bethesda, MD, 20892-1003, USA. sanjay.telu@nih.gov.ORCID 0000-0001-5300-8725
Susovan JanaMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, 10 Center Drive, Bethesda, MD, 20892-1003, USA.ORCID 0000-0001-9910-347X
Cheryl L MorseMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, 10 Center Drive, Bethesda, MD, 20892-1003, USA.ORCID 0000-0001-6213-3560
Victor W PikeMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, 10 Center Drive, Bethesda, MD, 20892-1003, USA. pikev@mail.nih.gov.ORCID 0000-0001-9032-2553

Funding

PET Radiopharmaceutical SciencesZIAMH002793 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI PIKE, VICTOR W · 2009 to 2025
$69.8M
Translational Evaluation Of PET RadiotracersZIAMH002795 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI INNIS, ROBERT · 2009 to 2025
$32.0M
Intramural NIH HHS ZIA MH002793Intramural NIH HHS ZIA MH002795U.S. Department of Health & Human Services | National Institutes of Health (NIH) ZIAMH002795
6 · The paper itself

Abstract

The 2,2,2-trifluoroethoxy group increasingly features in drugs and potential tracers for biomedical imaging with positron emission tomography (PET). Herein, we describe a rapid and transition metal-free conversion of fluoroform with paraformaldehyde into highly reactive potassium 2,2,2-trifluoroethoxide (CF

Indexed as

Positron-Emission TomographyCarbon RadioisotopesFluorine RadioisotopesFormaldehydeHumansPolymersPotassiumRadiopharmaceuticalsCarbon-11Carbon RadioisotopesFluorine-18Fluorine RadioisotopesFormaldehydeparaformPolymersPotassiumRadiopharmaceuticals

Identifiers

PMID38987549
PMCPMC11237122

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.