Evidence map›Paper›PMID 38987454›Full record

SynthesisObesity surgery2024

Liraglutide for the Treatment of Weight Regain After Bariatric Surgery: A Systematic Review and Meta-analysis.

Francisco Cezar Aquino de Moraes, Victoria Morbach, Vitor Kendi Tsuchiya Sano, Lilianne Rodrigues Fernandes, Michele Kreuz, Francinny Alves Kelly

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Obesity surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. The Evolving Role of Weight Loss Pharmacotherapy.Gastroenterology & hepatology · 2025
    Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Francisco Cezar Aquino de MoraesDepartment of Medicine, Federal University of Pará, R. Augusto Corrêa, nº01 Guamá, Belém, Pará, 66073-005, Brazil. francisco.cezar2205@gmail.com.ORCID 0000-0003-0623-8135
Victoria MorbachFeevale University, Novo Hamburgo, Rio Grande Do Sul, 93510-235, Brazil.ORCID 0009-0003-0326-647X
Vitor Kendi Tsuchiya SanoDepartment of Medicine, Federal University of Acre, Rio Branco, Acre, 69920-900, Brazil.ORCID 0000-0001-8317-1857
Lilianne Rodrigues FernandesAfya Abaetetuba, Abaetetuba, Pará, 68440-000, Brazil.ORCID 0000-0003-2054-4147
Michele KreuzLutheran University of Brazil, Canoas, Rio Grande Do Sul, 92425-020, Brazil.ORCID 0009-0009-8968-8190
Francinny Alves KellyDante Pazzanese Institute of Cardiology, São Paulo, São Paulo, 04012-909, Brazil.ORCID 0000-0003-0706-6929

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe efficacy of liraglutide for treating type 2 diabetes mellitus and obesity is well established, but their role in the treatment of weight regain after bariatric surgery remains unclear.

methodsWe searched PubMed, Embase, and Cochrane Library databases in January 2024. A random-effects model was employed to compute mean differences (MD) and events per 100 observations with 95% confidence intervals (CI) for continuous and binary endpoints. Statistical analysis was performed using R software.

resultsA total of 16 studies were included and 881 individuals. Patients were mostly female (50%), aged 36 to 55 years, with a mean body mass index (BMI) of 39.4 kg/m

conclusionsOur findings support the use of liraglutide for weight management in patients who experience weight regain after BS. Liraglutide is well tolerated and promotes significant weight loss, providing clinicians with a therapeutic option for this clinical challenge.

Indexed as

Bariatric SurgeryLiraglutideObesity, MorbidWeight GainWeight LossAdultBody Mass IndexDiabetes Mellitus, Type 2FemaleHumansMaleMiddle AgedTreatment OutcomeLiraglutideBariatric surgeryBMI reductionGLP-1 agonistsLiraglutidePost-bariatric surgerySevere obesityWeight regain

Identifiers

PMID38987454

What OpenQuestion holds

Texttitle and abstract
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.