ArticleBMJ open2024
Associations of hypertension, diabetes and heart disease risk with body mass index in older Chinese adults: a population-based cohort study.
Article in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Clinical obesity in Asian people: bridging the gap between adiposity and disease.Nature reviews. Endocrinology · 2026Review
- Effects of adiposity, insulin resistance, and inflammation on cardiometabolic multimorbidity: insights from interaction analyses and metabolic phenotyping in the China health and retirement longitudinal study 2011-2018.Cardiovascular diabetology · 2026Article
- Association of Obesity and Dietary Quality with Self-Reported Cardiovascular Disease Among Chinese Adults: A Cross-Sectional Study.Nutrients · 2026Article
- The association of triglyceride-glucose and triglyceride-glucose related indices with the risk of heart disease in a national.Cardiovascular diabetology · 2025Article
- Article
- Body Mass Index and the Risk of Hypertension-Diabetes Comorbidity in Elderly Population: A Prospective Cohort in China.Global heart · 2025Observational
- Postoperative complications in patients with Behçet's disease.Clinical rheumatology · 2024Article
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Authors and funding
5 authors.
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Abstract
objectiveObesity is a well-established risk factor for disease. Controversy exists regarding the relative risk of morbidity and mortality in individuals who are overweight or underweight compared with individuals with a normal body mass index (BMI). In this study, we investigated the associations between BMI and three non-communicable diseases (hypertension, diabetes and heart disease) in older adults.
designCohort study.
settingThis study used data from the China Health and Retirement Longitudinal Study. The baseline survey was carried out in 2011, and follow-up surveys were conducted in 2013, 2015 and 2018.
participantsParticipants who reported having no doctor-diagnosed chronic disease at baseline were included in this study.
main outcome measuresWe analysed the association between baseline BMI and disease incidence using Cox proportional hazards models. Disease information included self-reported diagnosed conditions. BMI was categorised according to the standard Chinese criteria: underweight (<18.5 kg/m
resultsA total of 5605 participants were included at baseline. Based on the Kaplan-Meier estimation, the participants who were obese had the highest incidence of all three diseases. Compared with normal weight participants, overweight participants had a greater disease incidence (log-rank tests are p<0.01). Cox regression models showed that with increasing BMI, the HRs of diseases increased accordingly (eg, for hypertension, compared with the BMI group <18.5 kg/m
conclusionA higher BMI was associated with an increased risk of hypertension, diabetes and heart disease in the population aged 45 years and older. Even within normal BMI ranges, a higher BMI was associated with an increased risk of disease. Actions are urgently needed at the population level to address the growing public health challenge of excess weight in the context of an ageing population.
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