Evidence map›Paper›PMID 38986540›Full record

SynthesisBMJ paediatrics open2024

Infection in preterm infants receiving topical emollient oil massage: a systematic review and meta-analysis of randomised control trials.

Fekadeselassie Belege Getaneh, Aden Asmare, Bezabih Abayneh, Endalk Birre, Anissa Mohammed, Amare Muche, Alemu Gedefie, Yibeltal Asmamaw, Zemen Mengesha, Natnael Moges and 3 more

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMJ paediatrics open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Fekadeselassie Belege GetanehPediatrics and child health nursing, Wollo University, Dessie, Ethiopia fekadebelege@gmail.com.ORCID http://orcid.org/0000-0001-8729-1784
Aden AsmareNICU, Dessie Hospital, Desse, Ethiopia.
Bezabih AbaynehDebre Berhan University, Debre Berhan, Amhara, Ethiopia.
Endalk BirrePediatrics and child health nursing, Wollo University, Dessie, Ethiopia.
Anissa MohammedPublic health, Wollo University, Dessie, Ethiopia.
Amare MuchePublic health, Wollo University, Dessie, Ethiopia.
Alemu GedefieMedical Laboratory, Wollo University, Dessie, Ethiopia.
Yibeltal AsmamawPediatrics and child health nursing, Wollo University, Dessie, Ethiopia.
Zemen MengeshaNursing, Wollo University, Dessie, Ethiopia.
Natnael MogesPediatrics and child health Nursing, Debre Tabor Univeristy, Debre Tabor, Ethiopia.
Dires Mihretie BirhanuPediatrics and child health nursing, Dilla University College of Health Sciences, Dilla, Ethiopia.ORCID http://orcid.org/0000-0002-1492-3733
Zebenay Workneh BitewPediatrics and child health nursing, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Asressie MollaPublic health, Wollo University, Dessie, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPreterm infants are highly susceptible to infections, which significantly contribute to morbidity and mortality. This systematic review and meta-analysis investigated the effectiveness of topical emollient oil application in preventing infections among preterm infants.

methodsA comprehensive search was conducted across multiple electronic databases (PubMed, Cochrane, Scopus, Clinical trials, Epistemonikos, HINARI and Global Index Medicus) and other sources. A total of 2185 articles were identified and screened for eligibility. The quality of included studies was assessed using the Cochrane Risk of Bias Tool for randomised controlled trials. Data analysis was performed using StataCrop MP V.17 software. Heterogeneity among the studies was evaluated using the I

resultsOf 2185 retrieved articles from initial searches, 11 met eligibility criteria and were included in the final analysis. A random effects meta-analysis revealed that infants who received massages with emollient oils had a 21% reduced risk of infection (risk ratio=0.79, 95% CI 0.64 to 0.97, I

conclusionIt is quite evident from this analysis that topical emollient oil application in preterm neonates is most likely effective in preventing infection. However, further studies, particularly from the African continent, are warranted to support universal recommendations.

Indexed as

EmollientsInfant, PrematureMassageRandomized Controlled Trials as TopicAdministration, TopicalHumansInfant, NewbornInfant, Premature, DiseasesEmollientsEpidemiologyNeonatologyNursing Care

Identifiers

PMID38986540
PMCPMC11243225

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.