Evidence map›Paper›PMID 38986439›Full record

ArticleImmunity2024

Skin deep: Epithelial cell metabolism and chronic skin inflammation.

Eliana R Solis, Julie M Jameson

Abstract readComment
PubMed Publisher
In one paragraph

Article in Immunity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Eliana R SolisDepartment of Biological Sciences, California State University, San Marcos, CA 92096, USA.
Julie M JamesonDepartment of Biological Sciences, California State University, San Marcos, CA 92096, USA. Electronic address: jjameson@csusm.edu.

Funding

CCR6 as a Regulatory Switch for Epidermal gamma delta T Cell Function in Wound RepairR15DK127440 · NIDDK · CALIFORNIA STATE UNIVERSITY SAN MARCOS · PI JAMESON, JULIE M · 2021 to 2021
$447k
NIDDK NIH HHS R15 DK127440
6 · The paper itself

Abstract

Skin inflammation is potentiated by coordinated epithelial and immune cell metabolism. In this issue of Immunity, Subudhi and Konieczny et al. delineate how HIF1α regulates epithelial cell glycolysis during psoriasis. In turn, lactate is a byproduct that augments type 17 γδ T cell responses to sustain inflammatory skin disease.

Indexed as

Epithelial CellsGlycolysisHypoxia-Inducible Factor 1, alpha SubunitPsoriasisSkinAnimalsChronic DiseaseHumansInflammationHypoxia-Inducible Factor 1, alpha Subunit

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.