Evidence map›Paper›PMID 38985887›Full record

ArticleThe British journal of surgery2024

Minimally Invasive transCervical oEsophagectomy (MICE) for oesophageal cancer: prospective cohort study (IDEAL stage 2A).

Richard J M T Vercoulen, Linde van Veenendaal, Irene F Kramer, Merlijn Hutteman, Atsushi Shiozaki, Hitoshi Fujiwara, Camiel Rosman, Bastiaan R Klarenbeek

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Article in The British journal of surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Richard J M T VercoulenDepartment of Surgery, Radboud University Medical Centre, Nijmegen, The Netherlands.
Linde van VeenendaalDepartment of Surgery, Radboud University Medical Centre, Nijmegen, The Netherlands.
Irene F KramerDepartment of Surgery, Radboud University Medical Centre, Nijmegen, The Netherlands.
Merlijn HuttemanDepartment of Surgery, Radboud University Medical Centre, Nijmegen, The Netherlands.
Atsushi ShiozakiDepartment of Surgery, Kyoto Prefectural University of Medicine Hospital, Kyoto, Japan.
Hitoshi FujiwaraDepartment of Surgery, Kyoto Prefectural University of Medicine Hospital, Kyoto, Japan.
Camiel RosmanDepartment of Surgery, Radboud University Medical Centre, Nijmegen, The Netherlands.ORCID 0000-0002-9152-3987
Bastiaan R KlarenbeekDepartment of Surgery, Radboud University Medical Centre, Nijmegen, The Netherlands.ORCID 0000-0003-2178-8557

Funding

Medtronic
6 · The paper itself

Abstract

backgroundMinimally invasive transcervical oesophagectomy is a surgical technique that offers radical oesophagectomy without the need for transthoracic access. The aim of this study was to evaluate the safety and feasibility of the minimally invasive transcervical oesophagectomy procedure and to report the refinement of this technique in a Western cohort.

methodsA single-centre prospective cohort study was designed as an IDEAL stage 2A study. Patients with oesophageal cancer (cT1b-4a N0-3 M0) who were scheduled for oesophagectomy with curative intent were eligible for inclusion in the study. The main outcome parameter was the postoperative pulmonary complication rate and the secondary outcomes were the anastomotic leakage, recurrent laryngeal nerve palsy, and R0 resection rates, as well as the lymph node yield.

resultsIn total, 75 patients underwent minimally invasive transcervical oesophagectomy between January 2021 and November 2023. Several modifications to the surgical technique were registered, evaluated, and implemented in the context of IDEAL stage 2A. A total of 12 patients (16%) had postoperative pulmonary complications, including pneumonia (4 patients) and pleural effusion with drainage or aspiration (8 patients). Recurrent laryngeal nerve palsy was observed in 33 of 75 patients (44%), with recovery in 30 of 33 patients (91%). A total of 5 of 75 patients (7%) had anastomotic leakage. The median number of resected lymph nodes was 29 (interquartile range 22-37) and the R0 resection rate was 96% (72 patients).

conclusionIntroducing minimally invasive transcervical oesophagectomy for oesophageal cancer in a Dutch institution is associated with a low rate of postoperative pulmonary complications and a high rate of temporary recurrent laryngeal nerve palsy.

Indexed as

Esophageal NeoplasmsEsophagectomyMinimally Invasive Surgical ProceduresPostoperative ComplicationsAgedFeasibility StudiesFemaleHumansMaleMiddle AgedNeoplasm StagingProspective Studies

Identifiers

PMID38985887
PMCPMC11235329

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.