Evidence map›Paper›PMID 38985862›Full record

ArticleScience advances2024

Targeting a microbiota

Guillaume Hoffmann, Maria Lukarska, Rachel H Clare, Ellen K G Masters, Kelly L Johnston, Louise Ford, Joseph D Turner, Steve A Ward, Mark J Taylor, Malene Ringkjøbing Jensen and 1 more

Abstract read
In one paragraph

Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Guillaume HoffmannInstitute for Advanced Biosciences (IAB), Structural Biology of Novel Drug Targets in Human Diseases, INSERM U1209, CNRS UMR 5309, Université Grenoble-Alpes, Grenoble 38000, France.ORCID 0000-0002-1143-0407
Maria LukarskaInstitute for Advanced Biosciences (IAB), Structural Biology of Novel Drug Targets in Human Diseases, INSERM U1209, CNRS UMR 5309, Université Grenoble-Alpes, Grenoble 38000, France.ORCID 0000-0002-6391-6732
Rachel H ClareCentre for Drugs and Diagnostics, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool L3 5QA, UK.ORCID 0000-0002-3945-0530
Ellen K G MastersCentre for Drugs and Diagnostics, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool L3 5QA, UK.
Kelly L JohnstonCentre for Drugs and Diagnostics, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool L3 5QA, UK.ORCID 0000-0002-5861-2646
Louise FordCentre for Drugs and Diagnostics, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool L3 5QA, UK.ORCID 0000-0001-7919-2866
Joseph D TurnerCentre for Drugs and Diagnostics, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool L3 5QA, UK.ORCID 0000-0002-2185-5476
Steve A WardCentre for Drugs and Diagnostics, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool L3 5QA, UK.ORCID 0000-0003-2331-3192
Mark J TaylorCentre for Drugs and Diagnostics, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool L3 5QA, UK.ORCID 0000-0003-3396-9275
Malene Ringkjøbing JensenUniversité Grenoble Alpes, CEA, CNRS, IBS, Grenoble, France.ORCID 0000-0003-0419-2196
Andrés PalenciaInstitute for Advanced Biosciences (IAB), Structural Biology of Novel Drug Targets in Human Diseases, INSERM U1209, CNRS UMR 5309, Université Grenoble-Alpes, Grenoble 38000, France.ORCID 0000-0002-1805-319X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The interplay between humans and their microbiome is crucial for various physiological processes, including nutrient absorption, immune defense, and maintaining homeostasis. Microbiome alterations can directly contribute to diseases or heighten their likelihood. This relationship extends beyond humans; microbiota play vital roles in other organisms, including eukaryotic pathogens causing severe diseases. Notably,

Indexed as

MicrobiotaWolbachiaAmino Acyl-tRNA SynthetasesAnimalsBoron CompoundsCrystallography, X-RayHumansLeucine-tRNA LigaseModels, MolecularSymbiosisAmino Acyl-tRNA SynthetasesBoron CompoundsLeucine-tRNA Ligase

Identifiers

PMID38985862
PMCPMC11235159

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.