Evidence map›Paper›PMID 38985841›Full record

ReviewAnnual review of cell and developmental biology2024

Evolution of Sensory Receptors.

Wendy A Valencia-Montoya, Naomi E Pierce, Nicholas W Bellono

Abstract readReview
In one paragraph

Review in Annual review of cell and developmental biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Convergent motifs of early olfactory processing are recapitulated by layer-wise efficient coding.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Article
  7. Article
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  10. Article
  11. Article
  12. Article
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  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Wendy A Valencia-MontoyaDepartment of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts, USA; email: wvalenciamontoya@g.harvard.edu, nbellono@harvard.edu.
Naomi E PierceDepartment of Organismic and Evolutionary Biology and Museum of Comparative Zoology, Harvard University, Cambridge, Massachusetts, USA.
Nicholas W BellonoDepartment of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts, USA; email: wvalenciamontoya@g.harvard.edu, nbellono@harvard.edu.

Funding

Structural Basis for Sensory Receptor FunctionR01NS129060 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Nicholas Bellono, Ryan E Hibbs · 2022 to 2026
$2.9M
Molecular Mechanisms of Integrative Signal TransductionR35GM142697 · NIGMS · HARVARD UNIVERSITY · PI Nicholas Bellono · 2021 to 2026
$2.6M
NIGMS NIH HHS R35 GM142697NINDS NIH HHS R01 NS129060
6 · The paper itself

Abstract

Sensory receptors are at the interface between an organism and its environment and thus represent key sites for biological innovation. Here, we survey major sensory receptor families to uncover emerging evolutionary patterns. Receptors for touch, temperature, and light constitute part of the ancestral sensory toolkit of animals, often predating the evolution of multicellularity and the nervous system. In contrast, chemoreceptors exhibit a dynamic history of lineage-specific expansions and contractions correlated with the disparate complexity of chemical environments. A recurring theme includes independent transitions from neurotransmitter receptors to sensory receptors of diverse stimuli from the outside world. We then provide an overview of the evolutionary mechanisms underlying sensory receptor diversification and highlight examples where signatures of natural selection are used to identify novel sensory adaptations. Finally, we discuss sensory receptors as evolutionary hotspots driving reproductive isolation and speciation, thereby contributing to the stunning diversity of animals.

Indexed as

Biological EvolutionSensory Receptor CellsAnimalsChemoreceptor CellsHumanschemoreceptorsion channelslight receptorsmechanoreceptorssensory drivethermoreceptors

Identifiers

PMID38985841
PMCPMC11526382

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.