Evidence map›Paper›PMID 38985793›Full record

ArticlePloS one2024

Mentha longifolia assisted nanostructures: An approach to obliterate microbial biofilms.

Mahwish Batool Kazmi, Hayfa Habes Almutairi, Ayesha Andleeb, Raheela Jabeen, Ghulam Mustafa, Umm-E- Habiba, Safdar Abbas Kazmi, Farah Naz, Najma Qammar

Abstract read
In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Mapping the knowledge landscape ofFrontiers in cellular and infection microbiology · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mahwish Batool KazmiDepartment of Biochemistry & Biotechnology, The Women University Multan, Punjab, Pakistan.
Hayfa Habes AlmutairiDepartment of Chemistry, College of Science, King Faisal University, Al-Ahsa, Saudi Arabia.ORCID 0000-0003-4284-2436
Ayesha AndleebDepartment of Biochemistry & Biotechnology, The Women University Multan, Punjab, Pakistan.
Raheela JabeenDepartment of Biochemistry & Biotechnology, The Women University Multan, Punjab, Pakistan.
Ghulam MustafaDepartment of Biochemistry, Government College University Faisalabad, Faisalabad, Punjab, Pakistan.ORCID 0000-0001-6510-6496
Umm-E- HabibaDepartment of Biochemistry & Biotechnology, The Women University Multan, Punjab, Pakistan.
Safdar Abbas KazmiDepartment of Environmental Science, COMSATS, Abbottabad Campus, Abbottabad, Pakistan.
Farah NazDepartment of Statistics, The Women University Multan, Punjab, Pakistan.
Najma QammarDepartment of Biochemistry, Bahauddin Zakariya University, Multan, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microbes maneuver strategies to become incessant and biofilms perfectly play a role in scaling up virulence to cause long-lasting infections. The present study was designed to assess the use of an eco-friendly formulation of functionalized silver nanoparticles generated from Mentha longifolia leaf extract (MℓE) for the treatment of biofilm-producing microbes. Nanoparticles synthesized using MℓE as a reducing agent were optimized at different strengths of AgNO3 (1 mM, 2 mM, 3 mM, and 4 mM). Synthesis of M. longifolia silver nanoparticles (MℓAgNPs) was observed spectrophotometrically (450 nm) showing that MℓAgNPs (4 mM) had the highest absorbance. Various techniques e.g., Fourier transforms Infrared spectroscopy (FTIR), Dynamic light scattering (DLS), zeta potential (ZP), X-ray Diffraction (XRD), scanning electron microscope (SEM), and transmission electron microscope (TEM) were used to characterize MℓAgNPs. In the present study, the Kirby-Bauer method revealed 4mM was the most detrimental conc. of MℓAgNPs with MIC and MBC values of 0.62 μg/mL and 1.25 μg/mL, 0.03 μg/mL and 0.078 μg/mL, and 0.07 μg/mL and 0.15 μg/mL against previously isolated and identified clinical strains of Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, and Staphylococcus aureus, respectively. Moreover, the MℓAgNP antibiofilm activity was examined via tissue culture plate (TCP) assay that revealed biofilm inhibition of up to 87.09%, 85.6%, 83.11%, and 75.09% against E. coli, P. aeruginosa, K. pneumonia, and S. aureus, respectively. Herbal synthesized silver nanoparticles (MℓAgNPs) tend to have excellent antibacterial and antibiofilm properties and are promising for other biomedical applications involving the extrication of irksome biofilms. For our best knowledge, it is the first study on the use of the green-synthesized silver nanoparticle MℓAgNP as an antibiofilm agent, suggesting that this material has antibiotic, therapeutic, and industrial applications.

Indexed as

Anti-Bacterial AgentsBiofilmsMenthaMetal NanoparticlesMicrobial Sensitivity TestsPlant ExtractsSilverStaphylococcus aureusEscherichia coliNanostructuresPlant LeavesPseudomonas aeruginosaX-Ray DiffractionAnti-Bacterial AgentsPlant ExtractsSilver

Identifiers

PMID38985793
PMCPMC11236100

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.