Evidence map›Paper›PMID 38985746›Full record

ArticlePloS one2024

Multidimensional screening and intervention program for neurocognitive disorder in vascular and multimorbid outpatients: Study protocol for a randomized clinical trial.

Cira Fundarò, Nicolò Granata, Silvia Traversoni, Valeria Torlaschi, Roberto Maestri, Marina Maffoni, Paola Baiardi, Federica Grossi, Michelangelo Buonocore, Paola Gabanelli and 2 more

Registry-linked trialAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05954741 (Comparing the Effectiveness of Multidimensional Rehabilitation Programs for Cognitive Impairment in Comorbid Outpatients), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05954741 narecruitingnot on this map

Comparing the Effectiveness of Multidimensional Rehabilitation Programs for Cognitive Impairment in Comorbid Outpatients: a Randomized Controlled Trial

TypeinterventionalSponsorIstituti Clinici Scientifici Maugeri SpARan2024 to 2026Enrolled75ConditionsCognitive Impairment, Dementia, Comorbidities and Coexisting Conditions, Vascular DementiaArmsMotor rehabilitation alone, Motor rehabilitation and Cognitive rehabilitation (paper-based), Motor rehabilitation and cognitive rehabilitation (digital-based)
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Cira FundaròIstituti Clinici Scientifici Maugeri IRCCS, Neurophysiopathology Unit of Montescano Institute (PV), Pavia, Italy.ORCID 0000-0002-7810-8885
Nicolò GranataIstituti Clinici Scientifici Maugeri IRCCS, Psychology Unit of Montescano Institute (PV), Pavia, Italy.
Silvia TraversoniIstituti Clinici Scientifici Maugeri IRCCS, Neurophysiopathology Unit of Montescano Institute (PV), Pavia, Italy.
Valeria TorlaschiIstituti Clinici Scientifici Maugeri IRCCS, Psychology Unit of Montescano Institute (PV), Pavia, Italy.
Roberto MaestriIstituti Clinici Scientifici Maugeri IRCCS, Department of Biomedical Engineering of Montescano Institute (PV), Pavia, Italy.
Marina MaffoniIstituti Clinici Scientifici Maugeri IRCCS, Psychology Unit of Montescano Institute (PV), Pavia, Italy.ORCID 0000-0002-3360-7293
Paola BaiardiIstituti Clinici Scientifici Maugeri IRCCS, Direzione Scientifica Centrale of Pavia Institute, Pavia, Italy.
Federica GrossiIstituti Clinici Scientifici Maugeri IRCCS, Psychology Unit of Pavia Institute, Pavia, Italy.
Michelangelo BuonocoreIstituti Clinici Scientifici Maugeri IRCCS, Neurophysiopathology Unit of Montescano Institute (PV), Pavia, Italy.
Paola GabanelliIstituti Clinici Scientifici Maugeri IRCCS, Psychology Unit of Pavia Institute, Pavia, Italy.
Marina Rita ManeraIstituti Clinici Scientifici Maugeri IRCCS, Psychology Unit of Pavia Institute, Pavia, Italy.
Antonia PierobonIstituti Clinici Scientifici Maugeri IRCCS, Psychology Unit of Montescano Institute (PV), Pavia, Italy.ORCID 0000-0002-4678-781X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe heightened risk of dementia resulting from multiple comorbid conditions calls for innovative strategies. Engaging in physical and cognitive activities emerges as a protective measure against cognitive decline. This protocol aims to discuss a multidomain intervention targeting individuals with dementias secondary to cerebrovascular or other medical diseases, emphasizing an often underrepresented demographic.

methodsThis study primary objectives are: a) to identify patients affected by Neurocognitive disorder due to vascular disease or multiple etiologies (screening and diagnostic phase) and b) to evaluate the effectiveness of distinct rehabilitation protocols (intervention phase): motor training alone, paper-based cognitive rehabilitation combined with motor training, digital-based cognitive rehabilitation coupled with motor training. DISCUSSION: Identifying cognitive impairment beyond rigid neurological contexts can facilitate timely and targeted interventions. This protocol strives to address the complex interplay of cognitive decline and comorbidities through a multidimensional approach, providing insights that can shape future interventions and enhancing overall well-being in this vulnerable population.

trial registrationThe study has been registered on July 13, 2023 with the ClinicalTrials.gov NCT05954741 registration number (https://classic.clinicaltrials.gov/ct2/show/NCT05954741).

Indexed as

Cognitive DysfunctionAgedDementiaFemaleHumansMaleMass ScreeningMultimorbidityNeurocognitive DisordersOutpatientsRandomized Controlled Trials as Topic

Identifiers

PMID38985746
PMCPMC11236129

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.