Evidence map›Paper›PMID 38985548›Full record

ArticleJournal of the American Chemical Society2024

Cooperative Phosphine-Photoredox Catalysis Enables N-H Activation of Azoles for Intermolecular Olefin Hydroamination.

Kassandra Sedillo, Flora Fan, Robert R Knowles, Abigail G Doyle

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Boron-Mediated Hydroalkylation of Unactivated Olefins: AnJournal of the American Chemical Society · 2026
    Article
  7. Article
  8. Visible light promotes PACS catalysis · 2025
    Article
  9. Biomimetic Dehydrogenative Intermolecular Formal Allylic Amidation of Branched α-Olefins.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kassandra SedilloDepartment of Chemistry, Princeton University, Princeton, New Jersey 08544, United States.
Flora FanDepartment of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, United States.
Robert R KnowlesDepartment of Chemistry, Princeton University, Princeton, New Jersey 08544, United States.ORCID 0000-0003-1044-4900
Abigail G DoyleDepartment of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, United States.ORCID 0000-0002-6641-0833

Funding

New Synthetic Methods Enabled by Excited-State Redox ChemistryR35GM134893 · NIGMS · PRINCETON UNIVERSITY · PI Robert R Knowles · 2020 to 2026
$3.8M
New Directions in Nickel and Photoredox CatalysisR35GM126986 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Abigail Gutmann Doyle · 2018 to 2026
$3.7M
NMR Console and Prodigy CryoProbeS10OD028644 · OD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GARG, NEIL K · 2021 to 2021
$600k
NIGMS NIH HHS R35 GM126986NIGMS NIH HHS R35 GM134893NIH HHS S10 OD028644
6 · The paper itself

Abstract

Catalytic intermolecular olefin hydroamination is an enabling synthetic strategy that offers direct and atom-economical access to a variety of nitrogen-containing compounds from abundant feedstocks. However, despite numerous advances in catalyst design and reaction development, hydroamination of N-H azoles with unactivated olefins remains an unsolved problem in synthesis. We report a dual phosphine and photoredox catalytic protocol for the hydroamination of numerous structurally diverse and medicinally relevant N-H azoles with unactivated olefins. Hydroamination proceeds with high anti-Markovnikov regioselectivity and

Identifiers

PMID38985548
PMCPMC11268998

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.