Evidence map›Paper›PMID 38985375›Full record

ReviewThe Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology2024

Comparison of long-term clinical outcomes of bioabsorbable polymer versus durable polymer drug-eluting stents: a systematic review and meta-analysis.

Abdur Rehman, Ifra Eeman Ahmed, Ahmed Nouman, Rabia Irfan, Qareeha Rehman, Abdul Rehman Shah Syed, Syeda Javeria Zakir, Samar Mehdi, Maha Mushtaq Khosa, Satesh Kumar and 4 more

Abstract readReview
In one paragraph

Review in The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Abdur RehmanDepartment of Medicine, Shaikh Zayed Hospital, Lahore, Pakistan.
Ifra Eeman AhmedFederal Medical and Dental College, Islamabad, Pakistan.
Ahmed NoumanDepartment of Medicine, Shaikh Zayed Hospital, Lahore, Pakistan.
Rabia IrfanFederal Medical and Dental College, Rawalpindi, Pakistan.
Qareeha RehmanFederal Medical and Dental College, Rawalpindi, Pakistan.
Abdul Rehman Shah SyedDow University of Health Science (Medicine), Karachi, Pakistan.
Syeda Javeria ZakirDow University of Health Science (Medicine), Karachi, Pakistan.
Samar MehdiDepartment of Medicine, Shaikh Zayed Hospital, Lahore, Pakistan.
Maha Mushtaq KhosaQuetta Institute of Medical Sciences, Quetta, Pakistan.
Satesh KumarDepartment of Medicine, Shaheed Mohtarma Benazir Bhutto Medical College, Lyari, Karachi, Pakistan. kewlanisatish@gmail.com.
Mahima KhatriDow University of Health Science (Medicine), Karachi, Pakistan.
F N U SamiullahDepartment of Medicine, Shaheed Mohtarma Benazir Bhutto Medical College, Lyari, Karachi, Pakistan.
Tamam MohamadWayne State University, Detroit, MI, USA.
Giustino VarrassiPaolo Procacci Foundation (PPF), Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOne million individuals in the USA die from acute myocardial infarction (MI), which currently affects 3 million people globally. The available data about the early and late outcomes of both biodegradable polymer drug-eluting stents (BP-DES) and durable polymer drug-eluting stents exhibit inconsistency. We performed a meta-analysis comparing the safety and efficacy of BP-DES with DP-DES.

methodsPubMed, Google Scholar, EMBASE, Cochrane, Ovid Medline, and Clinical Trials.gov databases were used to find out studies comparing BP-DES to DP-DES. All the analyses used the random-effects model.

resultsA total of 18 studies were incorporated in this meta-analysis that involved 28,874 patients, out of which 11,997 received the BP Stent, and the rest of 16,578 received the DP stent. Thorough analyses revealed that the risk of all-cause death was significantly higher in the BP-DES group (5.4% vs 2.7%) (RR 1.22, p 0.02) for two years or less than two-year follow-up. For studies with more than two years of follow-up, all-cause death was 9.07% (599/6603) in BP-DES and 9.47% (531/5602) in the DP-DES group but failed to achieve statistically significant levels (RR 0.97, p 0.58).

conclusionsThe study revealed no clinically significant (P value was > 0.05) differences in all-cause death, cardiac death, target lesion revascularization (TLR), late stent thrombosis, device-oriented composite endpoint/target lesion failure (DOCE/TLF), myocardial infarction (MI), target vessel MI, target vessel revascularization (TVR), target vessel infarction (TVI) between BP-DES and DP-DES for more than two years of follow-up. Additionally, all-cause death was only outcomes which found to have a statistically significant difference for less than two years of follow-up, while remaining were statistically non-significant.

Indexed as

Bioabsorbable polymer BPDrug-eluting stentDurable polymer DP

Identifiers

PMID38985375
PMCPMC11236827

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.