ArticleMemorias do Instituto Oswaldo Cruz2024
Isolation and characterisation of Leishmania (Leishmania) infantum from cutaneous leishmaniasis patients in northeast Brazil.
Article in Memorias do Instituto Oswaldo Cruz, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- LABCG1 AffectsACS infectious diseases · 2026Article
- Atypical manifestations of leishmaniasis in the state of Mato Grosso: a clinical-epidemiological study at the Júlio Müller University Hospital (2013-2023).Revista da Sociedade Brasileira de Medicina Tropical · 2026Article
- Rare detection of dermalParasite epidemiology and control · 2025Article
- Insights into the transmission cycle of cutaneous leishmaniasis from an endemic community in rural Guatemala.Current research in parasitology & vector-borne diseases · 2025Article
- Unusual report of an immunocompetent patient with atypical cutaneous leishmaniasis caused by Leishmania (Leishmania) infantum in Minas Gerais, Brazil.Revista da Sociedade Brasileira de Medicina Tropical · 2025Article
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Authors and funding
8 authors.
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Abstract
backgroundIn Brazil, Leishmania (Leishmania) infantum is a widely distributed protozoan parasite. The human leishmaniasis caused by this species is often associated with visceral form. Tegumentary leishmaniasis (TL) cases due to L. (L.) infantum in the country are considered rare but may be underestimated. Although probably uncommon, these cases represent a new challenge to the prevention and control of leishmaniasis.
objectivesHere, we describe two distinct cases of TL with atypical clinical presentations caused by L. (L.) infantum. METHODS AND
findingsParasites were isolated from cutaneous lesions of the two patients and typed as L. (L.) infantum after sequencing of the ribosomal DNA internal transcribed spacer. The dermotropic L. (L.) infantum isolates were compared in terms of growth culture patterns, metacyclogenesis and in vitro infectivity in macrophages. MAIN
conclusionsThis study addresses the emergence of L. (L.) infantum as a causative agent of cutaneous disease in a visceral leishmaniasis hotspot located in northeast Brazil. The data presented provides novel information about the presence of dermotropic L. (L.) infantum in the country and demonstrates the infectivity potential of theses isolates.
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