ArticleEnvironmental science & technology2024
ICP-MS As a Contributing Tool to Nontarget Screening (NTS) Analysis for Environmental Monitoring.
Article in Environmental science & technology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Toward diagnostically relevant isotope-ratio biomarkers: what does MC-ICP-MS still need for standardized measurements?Analytical and bioanalytical chemistry · 2026Review
- Recent advances in hybrid nano-interfaces for environmental pollutant detection: design principles, signal transduction, and analytical performance.Mikrochimica acta · 2026Review
- HCl-selective ionization reactions for improved Cl detection robustness in post-inductively coupled plasma chemical ionization.Journal of analytical atomic spectrometry · 2026Article
- Challenges Associated With PFAS Detection Method in Africa.Environmental health insights · 2025Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Due to the increasing number of chemicals released into the environment, nontarget screening (NTS) analysis is a necessary tool for providing comprehensive chemical analysis of environmental pollutants. However, NTS workflows encounter challenges in detecting both known and unknown pollutants with common chromatography high-resolution mass spectrometry (HRMS) methods. Identification of unknowns is hindered by limited elemental composition information, and quantification without identical reference standards is prone to errors. To address these issues, we propose the use of inductively coupled plasma mass spectrometry (ICP-MS) as an element-specific detector. ICP-MS can enhance the confidence of compound identification and improve quantification in NTS due to its element-specific response and unambiguous chemical composition information. Additionally, mass balance calculations for individual elements (F, Br, Cl, etc.) enable assessment of total recovery of those elements and evaluation of NTS workflows. Despite its benefits, implementing ICP-MS in NTS analysis and environmental regulation requires overcoming certain shortcomings and challenges, which are discussed herein.
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Registered trials
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