Evidence map›Paper›PMID 38984642›Full record

Trial reportExperimental physiology2025

Effects of resistance exercise, collagen ingestion and circulating oestrogen concentration on collagen synthesis in a female athlete: A case report.

Joonsung Lee, Jonathan C Y Tang, John Dutton, Rachel Dunn, William D Fraser, Kevin Enright, David R Clark, Claire E Stewart, Robert M Erskine

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Experimental physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Trial
  4. Physiology and the Olympics.Experimental physiology · 2025
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Joonsung LeeSchool of Sport and Exercise Sciences, Liverpool John Moors University, Liverpool, UK.
Jonathan C Y TangBioanalytical Facility, Norwich Medical School, University of East Anglia, Norwich, UK.
John DuttonBioanalytical Facility, Norwich Medical School, University of East Anglia, Norwich, UK.
Rachel DunnBioanalytical Facility, Norwich Medical School, University of East Anglia, Norwich, UK.
William D FraserBioanalytical Facility, Norwich Medical School, University of East Anglia, Norwich, UK.
Kevin EnrightSchool of Sport and Exercise Sciences, Liverpool John Moors University, Liverpool, UK.
David R ClarkSchool of Health Sciences, Robert Gordon University, Aberdeen, UK.ORCID https://orcid.org/0000-0002-6661-6137
Claire E StewartSchool of Sport and Exercise Sciences, Liverpool John Moors University, Liverpool, UK.
Robert M ErskineSchool of Sport and Exercise Sciences, Liverpool John Moors University, Liverpool, UK.ORCID https://orcid.org/0000-0002-5705-0207

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated the effects of resistance exercise (RE), hydrolysed collagen (HC) ingestion and circulating oestrogen concentration on collagen synthesis in a naturally menstruating female CrossFit athlete. In a double-blind, randomised cross-over design, the participant (36 years; height 1.61 m; mass 82.6 kg) consumed 0 or 30 g HC prior to performing back-squat RE when endogenous circulating oestrogen concentration was low (onset of menses, OM) and high (late follicular phase, LF) during two consecutive menstrual cycles. Ten 5-mL blood samples were collected during each of the four interventions to analyse concentrations of serum 17β-oestradiol, and biomarkers of type I collagen turnover, that is serum procollagen type I N-terminal propeptide (PINP, a biomarker of collagen synthesis) and plasma β-isomerised C-terminal telopeptide of type I collagen (β-CTX, a biomarker of collagen breakdown), as well as the serum concentration of 18 collagen amino acids. 17β-Oestradiol concentration was 5-fold higher at LF (891 ± 116 pmol L

Indexed as

CollagenEstrogensExerciseResistance TrainingAdultAthletesBiomarkersCollagen Type ICross-Over StudiesDouble-Blind MethodEstradiolFemaleHumansPeptide FragmentsPeptidesProcollagenBiomarkersCollagenCollagen Type IEstradiolEstrogensPeptide FragmentsPeptidesProcollagenconnective tissuefemaleglycineoestrogenproline

Identifiers

PMID38984642
PMCPMC12575999

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.