Evidence map›Paper›PMID 38984290›Full record

ArticleFood chemistry: X2024

Development of a rapid and reliable method to simultaneously detect seven food allergens in processed foods using LC-MS/MS.

Akira Torii, Yusuke Seki, Ryoichi Sasano, Yoshiki Ishida, Kosuke Nakamura, Rie Ito, Yusuke Iwasaki, Ken Iijima, Hiroshi Akiyama

Abstract read
In one paragraph

Article in Food chemistry: X, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Akira ToriiNisshin Seifun Group Inc., 5-3-1 Tsurugaoka, Fujimino-City, Saitama 356-8511, Japan.
Yusuke SekiNisshin Seifun Group Inc., 5-3-1 Tsurugaoka, Fujimino-City, Saitama 356-8511, Japan.
Ryoichi SasanoHoshi University, School of Pharmacy and Pharmaceutical Sciences, Department of Analytical Chemistry, 2-4-41 Ebara, Shinagawa-ku, Tokyo 142-8501, Japan.
Yoshiki IshidaNisshin Seifun Group Inc., 5-3-1 Tsurugaoka, Fujimino-City, Saitama 356-8511, Japan.
Kosuke NakamuraNational Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki-City, Kanagawa 210-9501, Japan.
Rie ItoHoshi University, School of Pharmacy and Pharmaceutical Sciences, Department of Analytical Chemistry, 2-4-41 Ebara, Shinagawa-ku, Tokyo 142-8501, Japan.
Yusuke IwasakiHoshi University, School of Pharmacy and Pharmaceutical Sciences, Department of Analytical Chemistry, 2-4-41 Ebara, Shinagawa-ku, Tokyo 142-8501, Japan.
Ken IijimaNisshin Seifun Group Inc., 5-3-1 Tsurugaoka, Fujimino-City, Saitama 356-8511, Japan.
Hiroshi AkiyamaHoshi University, School of Pharmacy and Pharmaceutical Sciences, Department of Analytical Chemistry, 2-4-41 Ebara, Shinagawa-ku, Tokyo 142-8501, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rapid analysis of multiple food allergens is required to confirm the appropriateness of food allergen labelling in processed foods. This study aimed to develop a rapid and reliable method to simultaneously detect trace amounts of seven food allergenic proteins (wheat, buckwheat, milk, egg, crustacean, peanut, and walnut) in processed foods using LC-MS/MS. Suspension-trapping (S-Trap) columns and on-line automated solid-phase extraction were used to improve the complex and time-consuming pretreatment process previously required for allergen analysis using LC-MS/MS. The developed method enabled the simultaneous detection of selected marker peptides for specific proteins derived from seven food ingredients in five types of incurred samples amended with trace amounts of allergenic proteins. The limit of detection values of the method for each protein were estimated to be <1 mg/kg. The developed analytical approach is considered an effective screening method for confirming food allergen labelling on a wide range of processed foods.

Indexed as

Detection methodFood allergenLC-MS/MSPeptide markerProcessed foodSolid-phase extraction

Identifiers

PMID38984290
PMCPMC11231652

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.