Evidence map›Paper›PMID 38983840›Full record

ArticleWorld journal of radiology2024

Renal resistive index measurements by ultrasound in patients with liver cirrhosis: Magnitude and associations with renal dysfunction.

Himanshu Surya, Ramesh Kumar, Rajeev Nayan Priyadarshi, Sabbu Surya Prakash, Sudhir Kumar

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Article in World journal of radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Himanshu SuryaDepartment of Gastroenterology, All India Institute of Medical Sciences, Patna 801507, India.
Ramesh KumarDepartment of Gastroenterology, All India Institute of Medical Sciences, Patna 801507, India. docrameshkr@gmail.com.
Rajeev Nayan PriyadarshiDepartment of Radiodiagnosis, All India Institute of Medical Sciences, Patna 801507, India.
Sabbu Surya PrakashDepartment of Gastroenterology, All India Institute of Medical Sciences, Patna 801507, India.
Sudhir KumarDepartment of Gastroenterology, All India Institute of Medical Sciences, Patna 801507, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe hemodynamic alterations seen in liver cirrhosis lead to renal vasoconstriction, ultimately causing acute kidney injury (AKI). The renal resistive index (RRI) is the most common Doppler ultrasound variable for measuring intrarenal vascular resistance.

aimTo evaluate the association of the RRI with AKI in patients with liver cirrhosis and to identify risk factors for high RRI.

methodsThis was a prospective observational study, where RRI was measured using Doppler ultrasound in 200 consecutive hospitalized patients with cirrhosis. The association of RRI with AKI was studied. The receiver operating characteristic (ROC) curve analysis was utilized to determine discriminatory cut-offs of RRI for various AKI phenotypes. Multivariate analysis was conducted to determine the predictors of high RRI.

resultsThe mean patient age was 49.08 ± 11.68 years, with the majority (79.5%) being male; the predominant etiology of cirrhosis was alcohol (39%). The mean RRI for the study cohort was 0.68 ± 0.09, showing a progressive increase with higher Child-Pugh class of cirrhosis. Overall, AKI was present in 129 (64.5%) patients. The mean RRI was significantly higher in patients with AKI compared to those without it (0.72 ± 0.06

conclusionIn cirrhosis patients, RRI exhibited a significant association with AKI, effectively differentiated between AKI phenotypes, and predicted AKI mortality.

Indexed as

Acute kidney injuryCirrhosisHepatorenal syndromeRenal DopplerRenal resistive index

Identifiers

PMID38983840
PMCPMC11229947

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