Evidence map›Paper›PMID 38983677›Full record

ArticleFrontiers in chemistry2024

Anti-inflammatory effects of thymol: an emphasis on the molecular interactions through

Muhammad Torequl Islam, Mehedi Hasan Bappi, Md Shimul Bhuia, Siddique Akber Ansari, Irfan Aamer Ansari, Manik Chanda Shill, Tala Albayouk, Na'il Saleh, Mohamed El-Shazly, Heba A S El-Nashar

Abstract read
In one paragraph

Article in Frontiers in chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Muhammad Torequl IslamDepartment of Pharmacy, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj, Bangladesh.
Mehedi Hasan BappiDepartment of Pharmacy, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj, Bangladesh.
Md Shimul BhuiaDepartment of Pharmacy, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj, Bangladesh.
Siddique Akber AnsariDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Irfan Aamer AnsariDepartment of Drug Science and Technology, University of Turin, Turin, Italy.
Manik Chanda ShillDepartment of Pharmaceutical Sciences, North South University, Dhaka, Bangladesh.
Tala AlbayoukDepartment of Pharmaceutical Sciences, North South University, Dhaka, Bangladesh.
Na'il SalehDepartment of Chemistry, College of Science, United Arab Emirates University, Al Ain, United Arab Emirates.
Mohamed El-ShazlyDepartment of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.
Heba A S El-NasharDepartment of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thymol (THY), as the natural monoterpene phenol, acts against oxidative stress and inflammatory processes. This study aimed to evaluate the anti-inflammatory effects and possible molecular mechanisms of THY via formalin-induced mouse and egg albumin-induced chick models alongside molecular docking and molecular dynamic (MD) simulations. THY (7.5, 15, and 30 mg/kg) was investigated, compared to celecoxib and ketoprofen (42 mg/kg), as anti-inflammatory standards. THY dose-dependently and significantly (

Indexed as

cyclooxygenaseinflammationin silico studiesoxidative stressthymol

Identifiers

PMID38983677
PMCPMC11231963

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.