Evidence map›Paper›PMID 38983651›Full record

ArticleClinical kidney journal2024

Interaction of general obesity and abdominal obesity with frailty in patients with chronic kidney disease: a nationally representative analysis.

Changyuan Yang, Xindong Qin, Jiamei Qiu, Carla Maria Avesani, Qingqing Cai, Ai Xia, Yi Lu, Lingshan Shen, Ruolan Duan, Jingyi Zhong and 5 more

Abstract read
In one paragraph

Article in Clinical kidney journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Body roundness index and mortality risk in patients with chronic kidney disease: moving beyond the obesity paradox.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Changyuan YangState Key Laboratory of Traditional Chinese Medicine Syndrome, National Chronic Kidney Disease Clinical Research Base of Traditional Chinese Medicine, Department of Nephrology, Guangdong Provincial Hospital of Chinese Medicine, Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.ORCID https://orcid.org/0000-0001-7153-9159
Xindong QinState Key Laboratory of Traditional Chinese Medicine Syndrome, National Chronic Kidney Disease Clinical Research Base of Traditional Chinese Medicine, Department of Nephrology, Guangdong Provincial Hospital of Chinese Medicine, Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Jiamei QiuState Key Laboratory of Traditional Chinese Medicine Syndrome, National Chronic Kidney Disease Clinical Research Base of Traditional Chinese Medicine, Department of Nephrology, Guangdong Provincial Hospital of Chinese Medicine, Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Carla Maria AvesaniDivision of Renal Medicine and Baxter Novum, Department of Clinical Science, Intervention and Technology, Karolinska Institute, Stockholm, Sweden.ORCID https://orcid.org/0000-0002-4458-8358
Qingqing CaiDivision of Nephrology, Nanfang Hospital, Southern Medical University, National Clinical Research Center for Kidney Disease, State Key Laboratory of Organ Failure Research, Guangdong Provincial Institute of Nephrology, Guangdong Provincial Key Laboratory of Renal Failure Research, Guangzhou, China.
Ai XiaDepartment of Nephrology, Dongzhimen Hospital, First Affiliated Hospital of Beijing University of Chinese Medicine, Beijing, China.
Yi LuDivision of Nephrology, Third Affiliated Hospital, Southern Medical University, Guangzhou, China.ORCID https://orcid.org/0000-0002-7348-8903
Lingshan ShenState Key Laboratory of Traditional Chinese Medicine Syndrome, National Chronic Kidney Disease Clinical Research Base of Traditional Chinese Medicine, Department of Nephrology, Guangdong Provincial Hospital of Chinese Medicine, Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Ruolan DuanState Key Laboratory of Traditional Chinese Medicine Syndrome, National Chronic Kidney Disease Clinical Research Base of Traditional Chinese Medicine, Department of Nephrology, Guangdong Provincial Hospital of Chinese Medicine, Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Jingyi ZhongState Key Laboratory of Traditional Chinese Medicine Syndrome, National Chronic Kidney Disease Clinical Research Base of Traditional Chinese Medicine, Department of Nephrology, Guangdong Provincial Hospital of Chinese Medicine, Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Zhenhua YangState Key Laboratory of Traditional Chinese Medicine Syndrome, National Chronic Kidney Disease Clinical Research Base of Traditional Chinese Medicine, Department of Nephrology, Guangdong Provincial Hospital of Chinese Medicine, Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Xusheng LiuState Key Laboratory of Traditional Chinese Medicine Syndrome, National Chronic Kidney Disease Clinical Research Base of Traditional Chinese Medicine, Department of Nephrology, Guangdong Provincial Hospital of Chinese Medicine, Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Bengt LindholmDivision of Renal Medicine and Baxter Novum, Department of Clinical Science, Intervention and Technology, Karolinska Institute, Stockholm, Sweden.
Fuhua LuState Key Laboratory of Traditional Chinese Medicine Syndrome, National Chronic Kidney Disease Clinical Research Base of Traditional Chinese Medicine, Department of Nephrology, Guangdong Provincial Hospital of Chinese Medicine, Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Guobin SuState Key Laboratory of Traditional Chinese Medicine Syndrome, National Chronic Kidney Disease Clinical Research Base of Traditional Chinese Medicine, Department of Nephrology, Guangdong Provincial Hospital of Chinese Medicine, Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.ORCID https://orcid.org/0000-0001-5073-9848

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: General and abdominal obesity are prevalent, with established associations to frailty in the elderly. However, few studies have investigated these associations in patients with chronic kidney disease (CKD), yielding inconsistent results. Methods: This cross-sectional study analysed data from the National Health and Nutrition Examination Survey (NHANES 2003-2018). Frailty was evaluated by the 36-item frailty index. General obesity was defined as a body mass index (BMI) >30 kg/m Results: A total of 5604 adult patients (median age 71 years, 42% men) with CKD were included in this analysis, with a median estimated glomerular filtration rate of 57.3 ml/min/1.73 m Conclusions: There may be an interaction between general and abdominal obesity with frailty in patients with CKD. Interventions aimed at preventing frailty should consider both aspects.

Indexed as

body mass indexchronic kidney diseasefrailtyobesitywaist circumference

Identifiers

PMID38983651
PMCPMC11231580

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.