Evidence map›Paper›PMID 38983562›Full record

ReviewFrontiers in ophthalmology2022

Oxytocin and secretin receptors - implications for dry eye syndrome and ocular pain.

Jacqueline B Lopez, Chih-Chiun Chang, Yien-Ming Kuo, Matilda F Chan, Bryan J Winn

Abstract readReview
In one paragraph

Review in Frontiers in ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jacqueline B LopezDepartment of Ophthalmology, University of California, San Francisco, San Francisco, CA, United States.
Chih-Chiun ChangDepartment of Ophthalmology, University of California, San Francisco, San Francisco, CA, United States.
Yien-Ming KuoDepartment of Ophthalmology, University of California, San Francisco, San Francisco, CA, United States.
Matilda F ChanDepartment of Ophthalmology, University of California, San Francisco, San Francisco, CA, United States.
Bryan J WinnDepartment of Ophthalmology, University of California, San Francisco, San Francisco, CA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dry eye syndrome, a form of ocular surface inflammation, and chronic ocular pain are common conditions impacting activities of daily living and quality of life. Oxytocin and secretin are peptide hormones that have been shown to synergistically reduce inflammation in various tissues and attenuate the pain response at both the neuron and brain level. The oxytocin receptor (OXTR) and secretin receptor (SCTR) have been found in a wide variety of tissues and organs, including the eye. We reviewed the current literature of

Indexed as

anti-inflammatorydry eye syndromeocular painoxytocinsecretin

Identifiers

PMID38983562
PMCPMC11182124

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.