Evidence map›Paper›PMID 38983477›Full record

ArticleTranslational andrology and urology2024

Risk factors for hyponatremia associated with desmopressin use.

Jae Heon Kim, Hee Jo Yang, Sang Yeong Kim, Yun Seob Song

Abstract read
In one paragraph

Article in Translational andrology and urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jae Heon Kim *Department of Urology, Soonchunhyang University Seoul Hospital, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-4490-3610
Hee Jo Yang *Department of Urology, Soonchunhyang University Cheonan Hospital, Cheonan, Republic of Korea.ORCID https://orcid.org/0000-0002-7195-806X
Sang Yeong KimDepartment of Data Innovation, Soonchunhyang University Seoul Hospital, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-3630-0086
Yun Seob SongDepartment of Urology, Soonchunhyang University Seoul Hospital, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-0909-3341

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Nocturia is a urinary symptom that can significantly impact a patient's quality of life. Desmopressin is prescribed for adults with nocturia. However, desmopressin use is associated with hyponatremia. The objective of this study was to assess the rate of hyponatremia in patients prescribed desmopressin and associated risk factors. Methods: Study subjects were patients who were newly prescribed desmopressin 0.1 mg (tablet) between January 1, 2015 (the start of available data) and December 1, 2020. Factors such as patients' baseline characteristics, comorbidities, and concomitant medications were analyzed to compare risk factors for hyponatremia (≤135 mmol/dL). Results: A total of 918 adults were included in this study. The rate of hyponatremia was 4.4 % in patients with desmopressin. The hyponatremia group was older than non-hyponatremia group (71.0 Conclusions: Hyponatremia occurred in 4.4% of patients with desmopressin. Risk factors of hyponatremia were age, comorbidities, concurrent medication and decreased estimated glomerular filtration rate (eGFR) level. Thus, care should be taken when administering desmopressin to these patients.

Indexed as

complicationDesmopressinhyponatremia

Identifiers

PMID38983477
PMCPMC11228683

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.