ArticleWorld journal of gastrointestinal surgery2024
Risk factors associated with intraoperative persistent hypotension in pancreaticoduodenectomy.
Article in World journal of gastrointestinal surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Predictive role of the prognostic nutritional index for long-term prognosis among patients undergoing pancreatoduodenectomy: a meta-analysis.BMC surgery · 2025Pooled it
- Involvement of capillary endothelial dysfunction and decreased plasma calcium concentration in persistent severe hypotension during pancreaticoduodenectomy.BMC anesthesiology · 2026Article
- Relationship of intraoperative hypotension with major adverse cardiovascular events and acute kidney injury after pancreaticoduodenectomy.Frontiers in medicine · 2026Article
- Preoperative malnutrition is a risk factor for intraoperative hypotension in high-risk surgical patients: a propensity score-matched cohort study.Perioperative medicine (London, England) · 2025Article
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Authors and funding
9 authors.
Funding
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Abstract
backgroundIntraoperative persistent hypotension (IPH) during pancreaticoduodenectomy (PD) is linked to adverse postoperative outcomes, yet its risk factors remain unclear.
aimTo clarify the risk factors associated with IPH during PD, ensuring patient safety in the perioperative period.
methodsA retrospective analysis of patient records from January 2018 to December 2022 at the First Affiliated Hospital of Nanjing Medical University identified factors associated with IPH in PD. These factors included age, gender, body mass index, American Society of Anesthesiologists classification, comorbidities, medication history, operation duration, fluid balance, blood loss, urine output, and blood gas parameters. IPH was defined as sustained mean arterial pressure < 65 mmHg, requiring prolonged deoxyepinephrine infusion for > 30 min despite additional deoxyepinephrine and fluid treatments.
resultsAmong 1596 PD patients, 661 (41.42%) experienced IPH. Multivariate logistic regression identified key risk factors: increased age [odds ratio (OR): 1.20 per decade, 95% confidence interval (CI): 1.08-1.33] (
conclusionIPH during PD is independently associated with older age, prolonged surgery, increased blood loss, and lower plasma Ca
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