ArticleFrontiers in ophthalmology2023
Quantitative assessment of the choroidal vasculature in myopic macular degeneration with optical coherence tomographic angiography.
Article in Frontiers in ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- The Significance of OCTA in Studying Vessel Density and Retinal Thickness in Individuals with Myopia.Medicina (Kaunas, Lithuania) · 2025Article
- Macular vascular density changes in different stages of chronic primary angle-closure glaucoma.Frontiers in medicine · 2025Article
- Differences in macular structure and microvasculature between high myopia and non-high myopia.Frontiers in medicine · 2025Article
- Swept-source OCTA assessment of iris vasculature as a biomarker for myopic macular degeneration severity.Advances in ophthalmology practice and researchArticle
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: To assess and compare choroidal morphometric vascular parameters, using optical coherence tomographic angiography (OCTA), in highly myopic adults with and without myopic macular degeneration (MMD). Methods: This is a clinic-based observational study of 148 eyes with axial length (AL) ≥25mm, enrolled from the high myopia clinic of the Singapore National Eye Centre. MMD was graded from fundus photographs. Swept source OCT (SS-OCT) and OCTA were performed and assessed for choroidal layer thickness (CT) and choroidal vasculature (choroidal vessel density (CVD), choroidal branch area (CBA) and mean choroidal vessel width (MCVW)) in the different choroidal layers (overall choroidal layer (CL), medium-vessel choroidal layer (MVCL), large-vessel choroidal layer (LVCL)). Results: CT Conclusion: Decrease in choroidal vessel width, density and thickness, and an increase in vascular branching were observed in eyes with long AL. A thinner and denser choroid with greater branching area and vessel width, which may all be signs of hypoxia, were associated with greater odds of MMD2.
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