ArticleFrontiers in ophthalmology2023
MicroRNA-494 augments fibrotic transformation of human retinal pigment epithelial cells and targets p27 with cell-type specificity.
Article in Frontiers in ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Postpartum Plasma-Derived Exosomes Confer Mitochondrial Stabilization and Neuroprotection against Ischemic Stroke.Research square · 2026Article
- Assessment of a new class of slow γ-aminobutyric acid type A receptor anesthetic on mouse neuronal and astrocyte mitochondrial function.Research square · 2025Article
- Conditional neuronal deletion of microRNA-141/200c cluster, but not microRNA-181a/b-1 cluster, is protective against experimental stroke in male mice.Physiological reports · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Epiretinal membranes (ERMs) are the result of fibro-cellular proliferation that cause distortion and impairment of central vision. We hypothesized that select microRNAs (miRs) regulate retinal fibro-proliferation and ERM formation. Following IRB approval, a pilot study was performed in patients presenting for retina surgery with and without clinical ERMs. Total RNA was isolated from ERM tissue and controls from non-ERM vitreous and subjected to miR profiling
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Registered trials
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