Evidence map›Paper›PMID 38982708›Full record

ReviewACS biomaterials science & engineering2024

Research Progress of Hydrogel Microneedles in Wound Management.

Ming Ji, Fangbiao Zhan, Xingan Qiu, Hong Liu, Xuezhe Liu, Pengzhen Bu, Bikun Zhou, Maciej Serda, Qian Feng

Abstract readReview
In one paragraph

Review in ACS biomaterials science & engineering, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  18. A PIEZO-Gated Mechanotransduction Timing Window Governs Scar Commitment in Wound Healing.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ming JiDepartment of Orthopedics, Chongqing University Three Gorges Hospital, School of Medicine, Chongqing University, Chongqing 404000, China.
Fangbiao ZhanDepartment of Orthopedics, Chongqing University Three Gorges Hospital, School of Medicine, Chongqing University, Chongqing 404000, China.
Xingan QiuDepartment of Orthopedics, Chongqing University Three Gorges Hospital, School of Medicine, Chongqing University, Chongqing 404000, China.
Hong LiuDepartment of Orthopedics, Chongqing University Three Gorges Hospital, School of Medicine, Chongqing University, Chongqing 404000, China.ORCID 0000-0002-7534-1710
Xuezhe LiuKey Laboratory of Biorheological Science and Technology, Ministry of Educations, Collage of Bioengineering, Chongqing University, Chongqing 400044, China.ORCID 0000-0002-2467-9121
Pengzhen BuKey Laboratory of Biorheological Science and Technology, Ministry of Educations, Collage of Bioengineering, Chongqing University, Chongqing 400044, China.
Bikun ZhouKey Laboratory of Biorheological Science and Technology, Ministry of Educations, Collage of Bioengineering, Chongqing University, Chongqing 400044, China.
Maciej SerdaInstitute of Chemistry, University of Silesia in Katowice, Katowice 40-006, Poland.ORCID 0000-0003-4926-5782
Qian FengKey Laboratory of Biorheological Science and Technology, Ministry of Educations, Collage of Bioengineering, Chongqing University, Chongqing 400044, China.ORCID 0000-0003-3196-0840

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microneedles are a novel drug delivery system that offers advantages such as safety, painlessness, minimally invasive administration, simplicity of use, and controllable drug delivery. As a type of polymer microneedle with a three-dimensional network structure, hydrogel microneedles (HMNs) possess excellent biocompatibility and biodegradability and encapsulate various therapeutic drugs while maintaining drug activity, thus attracting significant attention. Recently, they have been widely employed to promote wound healing and have demonstrated favorable therapeutic effects. Although there are reviews about HMNs, few of them focus on wound management. Herein, we present a comprehensive overview of the design and preparation methods of HMNs, with a particular emphasis on their application status in wound healing, including acute wound healing, infected wound healing, diabetic wound healing, and scarless wound healing. Finally, we examine the advantages and limitations of HMNs in wound management and provide suggestions for future research directions.

Indexed as

Drug Delivery SystemsHydrogelsNeedlesWound HealingAnimalsHumansHydrogelsdrug deliveryhydrogel microneedleintelligentizationmicromoldingwound healing

Identifiers

PMID38982708
PMCPMC11322915

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.