Evidence map›Paper›PMID 38982624›Full record

ArticleESC heart failure2024

Cardiac power output ratio: Novel survival predictor after percutaneous ventricular assist device in cardiogenic shock.

Calvin Leung, Ivan Man Ho Wong, Cheuk Bong Ho, Michael Chi Shing Chiang, Yan Hang Fong, Pok Him Lee, Tai Chung So, Yin Kei Yeung, Chung Yin Leung, Yuet Wong Cheng and 5 more

Abstract read
In one paragraph

Article in ESC heart failure, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Calvin LeungDepartment of Medicine, Division of Cardiology, Queen Elizabeth Hospital, Hong Kong SAR.ORCID 0009-0006-8272-7976
Ivan Man Ho WongDepartment of Medicine, Division of Cardiology, Queen Elizabeth Hospital, Hong Kong SAR.
Cheuk Bong HoDepartment of Medicine, Division of Cardiology, Queen Elizabeth Hospital, Hong Kong SAR.
Michael Chi Shing ChiangDepartment of Medicine, Division of Cardiology, Queen Elizabeth Hospital, Hong Kong SAR.
Yan Hang FongDepartment of Medicine, Division of Cardiology, Queen Elizabeth Hospital, Hong Kong SAR.
Pok Him LeeDepartment of Medicine, Division of Cardiology, Queen Elizabeth Hospital, Hong Kong SAR.
Tai Chung SoDepartment of Medicine, Division of Cardiology, Queen Elizabeth Hospital, Hong Kong SAR.
Yin Kei YeungDepartment of Medicine, Division of Cardiology, Queen Elizabeth Hospital, Hong Kong SAR.
Chung Yin LeungDepartment of Medicine, Division of Cardiology, Queen Elizabeth Hospital, Hong Kong SAR.
Yuet Wong ChengDepartment of Medicine, Division of Cardiology, Queen Elizabeth Hospital, Hong Kong SAR.
Shing Fung ChuiDepartment of Medicine, Division of Cardiology, Queen Elizabeth Hospital, Hong Kong SAR.
Alan Ka Chun ChanDepartment of Medicine, Division of Cardiology, Queen Elizabeth Hospital, Hong Kong SAR.
Chi Yuen WongDepartment of Medicine, Division of Cardiology, Queen Elizabeth Hospital, Hong Kong SAR.
Kam Tim ChanDepartment of Medicine, Division of Cardiology, Queen Elizabeth Hospital, Hong Kong SAR.
Michael Kang Yin LeeDepartment of Medicine, Division of Cardiology, Queen Elizabeth Hospital, Hong Kong SAR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsCurrently, there is limited data on prognostic indicators after insertion of percutaneous ventricular assist device (PVAD) in the treatment of cardiogenic shock (CS). This study evaluated the prognostic role of cardiac power output (CPO) ratio, defined as CPO at 24 h divided by early CPO (30 min to 2 h), in CS patients after PVAD. METHODS AND

resultsConsecutive CS patients from the QEH-PVAD Registry were followed up for survival at 90 days after PVAD. Among 121 consecutive patients, 98 underwent right heart catheterization after PVAD, with CPO ratio available in 68 patients. The CPO ratio and 24-h CPO, but not the early CPO post PVAD, were significantly associated with 90-day survival, with corresponding area under curve in ROC analysis of 0.816, 0.740, and 0.469, respectively. In multivariate analysis, only the CPO ratio and lactate level at 24 h remained as independent survival predictors. The CPO ratio was not associated with age, sex, and body size. Patients with lower CPO ratio had significantly lower coronary perfusion pressure, worse right heart indices, and higher pulmonary vascular resistance. A lower CPO ratio was also significantly associated with mechanical ventilation and higher creatine kinase levels in myocardial infarction patients.

conclusionIn post-PVAD patients, the CPO ratio outperformed the absolute CPO values and other haemodynamic metrics in predicting survival at 90 days. Such a proportional change of CPO over time, likely reflecting native heart function recovery, may help to guide management of CS patients post-PVAD.

Indexed as

Cardiac OutputHeart-Assist DevicesShock, CardiogenicAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedPrognosisRegistriesRetrospective StudiesSurvival RateHaemodynamicsHeart recoveryImpellaMechanical circulatory support

Identifiers

PMID38982624
PMCPMC11631333

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.