Evidence map›Paper›PMID 38982571›Full record

Trial reportInternational journal of food sciences and nutrition2024

Weight, habitual fibre intake, and microbiome composition predict tolerance to fructan supplementation.

Jeffrey Letourneau, Benjamin C Neubert, Diana Dayal, Verónica M Carrion, Heather K Durand, Eric P Dallow, Sharon Jiang, Michelle Kirtley, Geoffrey S Ginsburg, P Murali Doraiswamy and 1 more

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in International journal of food sciences and nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jeffrey LetourneauDepartment of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, USA.
Benjamin C NeubertProgram in Computational Biology and Bioinformatics, Duke University School of Medicine, Durham, NC, USA.
Diana DayalSchool of Medicine, University of North Carolina, Chapel Hill, NC, USA.
Verónica M CarrionDuke Office of Clinical Research, Duke University, Durham, NC, USA.
Heather K DurandDepartment of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, USA.
Eric P DallowDepartment of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, USA.
Sharon JiangDepartment of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, USA.
Michelle KirtleyDepartment of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, USA.
Geoffrey S GinsburgDuke Center for Applied Genomics and Precision Medicine, Duke University Health System, Durham, NC, USA.
P Murali DoraiswamyDuke Center for Applied Genomics and Precision Medicine, Duke University Health System, Durham, NC, USA.
Lawrence A DavidDepartment of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, USA.

Funding

UNIV OF NORTH CAROLINA CLINICAL NUTRITION RESEARCH UNITP30DK056350 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Venkata Saroja Voruganti · 1999 to 2026
$31.6M
PILOT AND FEASIBILITY STUDIESP30DK034987 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ROBERT S. SANDLER · 1985 to 2026
$30.5M
Personalizing prebiotic therapies that target human gut microbiotaR01DK116187 · NIDDK · DUKE UNIVERSITY · PI Lawrence Anthony David · 2018 to 2026
$3.7M
Using DNA sequencing to assess dietary species richnessR01DK128611 · NIDDK · DUKE UNIVERSITY · PI Lawrence Anthony David · 2022 to 2026
$2.9M
NIDDK NIH HHS P30 DK034987NIDDK NIH HHS P30 DK056350NIDDK NIH HHS R01 DK116187NIDDK NIH HHS R01 DK128611
6 · The paper itself

Abstract

Fructans are commonly used as dietary fibre supplements for their ability to promote the growth of beneficial gut microbes. However, fructan consumption has been associated with various dosage-dependent side effects. We characterised side effects in an exploratory analysis of a randomised trial in healthy adults (

Indexed as

Dietary FiberDietary SupplementsFructansGastrointestinal MicrobiomeInulinAdultBody WeightFemaleFlatulenceHumansMaleMiddle AgedYoung AdultDietary FiberFructansInulinbioinformaticsdietary fibregastroenterologyinulinMicrobiome

Identifiers

PMID38982571
PMCPMC11491164

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.