Evidence map›Paper›PMID 38982442›Full record

ArticleBMC veterinary research2024

Toxicological insight of metiram: immuno-oxidative, neuro-behavioral, and hemato-biochemical changes during acute exposure of Nile tilapia (Oreochromis niloticus).

Mohamed Shaalan, Mohamed A Elbealy, Mahmoud I M Darwish, Elsayed M Younis, Abdelwahab A Abdelwarith, Asmaa I Abdelaty, Simon J Davies, Rowida E Ibrahim, Afaf N Abdel Rahman

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Article in BMC veterinary research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mohamed ShaalanDepartment of Pathology, Faculty of Veterinary Medicine, Cairo University, PO Box 12211, Giza, Egypt. mohamedibrahim@cu.edu.eg.
Mohamed A ElbealyDepartment of Aquatic Animal Medicine, Faculty of Veterinary Medicine, Mansoura University, PO Box 35516, Mansoura, Dakahlia, Egypt.
Mahmoud I M DarwishDepartment of Biochemistry and Molecular Biology, Medicine Faculty of Veterinary Medicine, Zagazig University, PO Box 44511, Zagazig, Egypt.
Elsayed M YounisDepartment of Zoology, College of Science, King Saud University, PO Box 2455, Riyadh, 11451, Saudi Arabia.
Abdelwahab A AbdelwarithDepartment of Zoology, College of Science, King Saud University, PO Box 2455, Riyadh, 11451, Saudi Arabia.
Asmaa I AbdelatyDepartment of Behaviour and Management of Animal, Poultry and Aquatics, Faculty of Veterinary Medicine, Zagazig University, PO Box 44511, Zagazig, Egypt.
Simon J DaviesAquaculture Nutrition Research Unit ANRU, Ryan Institute, College of Science and Engineering, Carna Research Station, University of Galway, Galway, H91V8Y1, Ireland.
Rowida E IbrahimDepartment of Aquatic Animal Medicine, Faculty of Veterinary Medicine, Zagazig University, PO Box 44511, Zagazig, Egypt. rowidakamhawey@yahoo.com.
Afaf N Abdel RahmanDepartment of Aquatic Animal Medicine, Faculty of Veterinary Medicine, Zagazig University, PO Box 44511, Zagazig, Egypt. afne56@gmail.com.

Funding

Researches Supporting, King Saud University, Riyadh, Saudi Arabia (RSP2024R36)
6 · The paper itself

Abstract

backgroundThe inappropriate use of pesticides including fungicides creates severe biological hazards that can endanger fish health and impede sustainable aquaculture.

objectiveThis study investigated the negative impacts of metiram (MET), a fungicide on the health status of Nile tilapia (Oreochromis niloticus) for a 96-hour duration as an acute exposure in a static renewal system.

methodsThree hundred fish (average body weight: 37.50 ± 0.22 g) were assigned into six groups (50 fish/group) with five replicates (10 fish/replicate). Fish were exposed to various six concentrations (0, 1.5, 3, 4.5, 6, and 7.5 mg/L) of MET as a water exposure to for 96-hour without water exchange. The fish's behavior, clinical signs, and mortalities were documented every day of the exposure period. Additionally, MET's impact on blood profile, stress biomarkers, hepato-renal functions, immune-antioxidant status, and brain biomarker were closely monitored.

resultsThe lethal concentration (LC

conclusionAccording to these findings, the 96-hour LC

Indexed as

CichlidsFungicides, IndustrialAnimalsBehavior, AnimalBiomarkersBrainLethal Dose 50Oxidative StressWater Pollutants, ChemicalBiomarkersFungicides, IndustrialWater Pollutants, ChemicalAcute exposureAquatic toxicologyBehaviourBlood pictureOreochromis niloticusPolyram DF

Identifiers

PMID38982442
PMCPMC11232312

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.