Evidence map›Paper›PMID 38982362›Full record

SynthesisBMC musculoskeletal disorders2024

The incidence of fractures in children under two years of age: a systematic review.

Karen Rosendahl, Laura Tanturri de Horatio, Celine Habre, Susan C Shelmerdine, Janina Patsch, Ola Kvist, Regina K Lein, Domen Plut, Edvard J Enoksen, Rien Avenarius and 6 more

Abstract readSystematic Review
In one paragraph

Synthesis in BMC musculoskeletal disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Karen RosendahlDepartment of Clinical Medicine, UiT the Artic University of Norway, Tromsø, Norway. karen.rosendahl@unn.no.
Laura Tanturri de HoratioDepartment of Clinical Medicine, UiT the Artic University of Norway, Tromsø, Norway.
Celine HabrePediatric Radiology Unit, Radiology Division, Diagnostic Department, University Hospitals of Geneva, Geneva, Switzerland.
Susan C ShelmerdineDepartment of Clinical Radiology, Great Ormond Street Hospital for Children NHS Foundation Trust, Great Ormond Street, London, England.
Janina PatschDivision of General and Pediatric Radiology, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Wien, Austria.
Ola KvistDepartment of Pediatric Radiology, Karolinska University Hospital, Stockholm, Sweden.
Regina K LeinUniversity Library, Bergen University, Bergen, Norway.
Domen PlutClinical Radiology Institute, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Edvard J EnoksenDepartment of Clinical Medicine, UiT the Artic University of Norway, Tromsø, Norway.
Rien AvenariusDepartment of Clinical Medicine, UiT the Artic University of Norway, Tromsø, Norway.
Lene B LaborieSection for Paediatric Radiology, Department of Radiology, Haukeland University Hospital, Bergen, Norway.
Thomas A AugdalDepartment of Clinical Medicine, UiT the Artic University of Norway, Tromsø, Norway.
Paolo SimoniDepartment of Radiology, "Reine Fabiola" Children's University Hospital Université Libre de Bruxelles, Brussels, Belgium.
Rick R van RijnDepartment of Radiology and Nuclear Medicine, UMC, University of Amsterdam, Amsterdam, Netherlands.
Amaka C OffiahDepartment of Oncology & Metabolism, University of Sheffield, Sheffield, England.
European Society of Paediatric Radiology (ESPR) Musculoskeletal and Child Abuse Task Forces

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEpidemiological research on fractures in children under the age of two is of great importance to help understand differences between accidental and abusive trauma.

objectiveThis systematic review aimed to evaluate studies reporting on the incidence of fractures in children under two years of age, excluding birth injuries. Secondary outcome measures included fracture location, mechanisms of injury and fracture characteristics.

methodsA systematic literature review (1946 to February 7th 2024), including prospective and retrospective cohort studies and cross-sectional cohort studies, was performed. Studies including children from other age groups were included if the actual measures for those aged 0-2 years could be extracted. We also included studies restricted to infants. Annual incidence rates of fractures were extracted and reported as the main result. Critical appraisal of was performed using the Appraisal tool for Cross-Sectional Studies.

resultsTwelve moderate to good quality studies met eligibility criteria, of which seven were based on data from medical records and five were registry studies. Studies investigated different aspects of fractures, making comprehensive synthesis challenging. There was an overall annual fracture incidence rate of 5.3 to 9.5 per 1,000 children from 0-2 years of age; with commonest sites being the radius/ulna (25.2-40.0%), followed by tibia/fibula (17.3-27.6%) and the clavicle (14.6-14.8%) (location based on 3 studies with a total of 407 patients). In infants, the reported incidence ranged between 0.7 to 4.6 per 1,000 (based on 3 studies), with involvement of the clavicle in 22.2% and the distal humerus in 22.2% of cases (based on 1 study). Only a single metaphyseal lesion was reported (proximal humerus of an 11-month-old infant). Fracture mechanisms were detailed in four studies, with fall from chair, bed, table, own height or fall following indoor activities causing 50-60% of fractures.

conclusionsThere is a paucity of good quality data on fracture incidence in children under the age of two. Larger, prospective and unbiased studies would be helpful in determining normal pattern of injuries, so that differences from abusive trauma may be better understood.

Indexed as

Fractures, BoneChild AbuseCross-Sectional StudiesHumansIncidenceInfantInfant, NewbornChildrenFractureIncidenceInfantPaediatric

Identifiers

PMID38982362
PMCPMC11232341

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.