Evidence map›Paper›PMID 38982304›Full record

ReviewNature reviews. Urology2025

Optimizing cystoscopy and TURBT: enhanced imaging and artificial intelligence.

Eugene Shkolyar, Steve R Zhou, Camella J Carlson, Shuang Chang, Mark A Laurie, Lei Xing, Audrey K Bowden, Joseph C Liao

Abstract readReview
In one paragraph

Review in Nature reviews. Urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. The Stalk Sign in Bladder Cancer: CEUS Versus MRI.Diagnostics (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Advances in the management of localized bladder cancers.Nature reviews. Clinical oncology · 2026
    Review
  10. Article
  11. Review
  12. Applications of AI in urology.Nature reviews. Urology · 2026
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Eugene ShkolyarDepartment of Urology, Stanford University School of Medicine, Stanford, CA, USA.
Steve R ZhouDepartment of Urology, Stanford University School of Medicine, Stanford, CA, USA.
Camella J CarlsonDepartment of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.ORCID 0000-0003-4937-2043
Shuang ChangDepartment of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.
Mark A LaurieDepartment of Urology, Stanford University School of Medicine, Stanford, CA, USA.
Lei XingDepartment of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, USA.ORCID 0000-0003-2536-5359
Audrey K BowdenDepartment of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.ORCID 0000-0002-5412-3976
Joseph C LiaoDepartment of Urology, Stanford University School of Medicine, Stanford, CA, USA. jliao@stanford.edu.ORCID 0000-0003-2448-5463

Funding

Dual Modality X-ray Luminescence CT for in vivo Cancer ImagingR01CA227713 · NCI · STANFORD UNIVERSITY · PI XING, LEI · 2019 to 2023
$2.9M
Intraoperative integration of artificial intelligence during cystoscopic surgeryR01CA260426 · NCI · STANFORD UNIVERSITY · PI JOSEPH C LIAO, Lei Xing · 2022 to 2026
$2.3M
Leveraging deep learning for markerless motion management in radiation therapyR01CA256890 · NCI · STANFORD UNIVERSITY · PI XING, LEI · 2021 to 2025
$2.1M
BCCMA: Basic and Translational Mechanisms of Cancer Initiation of the Urothelium in Veterans Exposed to Carcinogens: Leveraging Artificial Neural Networks to Enhance Detection of Carcinoma in situI01BX005598 · VA · VETERANS ADMIN PALO ALTO HEALTH CARE SYS · PI JOSEPH C LIAO · 2022 to 2026
–
BLRD VA I01 BX005598NCI NIH HHS R01 CA227713NCI NIH HHS R01 CA256890NCI NIH HHS R01 CA260426
6 · The paper itself

Abstract

Diagnostic cystoscopy in combination with transurethral resection of the bladder tumour are the standard for the diagnosis, surgical treatment and surveillance of bladder cancer. The ability to inspect the bladder in its current form stems from a long chain of advances in imaging science and endoscopy. Despite these advances, bladder cancer recurrence and progression rates remain high after endoscopic resection. This stagnation is a result of the heterogeneity of cancer biology as well as limitations in surgical techniques and tools, as incomplete resection and provider-specific differences affect cancer persistence and early recurrence. An unmet clinical need remains for solutions that can improve tumour delineation and resection. Translational advances in enhanced cystoscopy technologies and artificial intelligence offer promising avenues to overcoming the progress plateau.

Indexed as

Artificial IntelligenceCystoscopyUrinary Bladder NeoplasmsHumans

Identifiers

PMID38982304
PMCPMC11939114

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.