ArticleScientific reports2024
Osteoporosis, spinal degenerative disorders, and their association with low back pain, activities of daily living, and physical performance in a general population.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Causal links between multi-domain risk factors and intervertebral disc degeneration: a systematic review and meta-analysis of Mendelian randomization studies.BMC musculoskeletal disorders · 2026Pooled it
- Associations Between Sum Scores or Combinations of MRI Findings in the Lumbar Spine and Low Back Pain-Related Outcomes: A Systematic Review.European journal of pain (London, England) · 2025Pooled it
- Comparative Effects of Minodronate and Alendronate on Low Back Pain in Postmenopausal Osteoporosis and Age Influence: A Head-to-Head, Randomized Clinical Trial.Clinical interventions in aging · 2025Trial
- Detecting scoliosis at scale using automated Cobb angle analysis in the UK Biobank.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Mapping the genetically predicted associations between lower-extremity muscle traits and spinal diseases.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- A genomic structural equation modelling analysis of the shared genetic architecture of the aging spine.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Trends in prevalence and disability burden of main rheumatic and musculoskeletal diseases in France 2008-2022.RMD open · 2026Article
- The impact of pedicle screw transitional segment and thread distribution on postoperative rod-screw system failure : insights from clinical research and mechanical testing.Bone & joint research · 2026Article
- Single-incision four-level oblique lateral interbody fusion and cement-augmented fixation in a severely osteoporotic lumbar spine: a case report.Journal of spine surgery (Hong Kong) · 2026Article
- Associations between single and combined lumbar MRI findings and low back pain with and without leg pain: a cross-sectional study.BMC musculoskeletal disorders · 2026Article
- Construction and validation of a nomogram predictive model for safety-related influencing factors in unilateral paracentesis kyphoplasty for spinal compression fractures.European journal of medical research · 2026Article
- Knowledge, attitudes, and practice regarding rehabilitation among postoperative patients with spinal degenerative diseases: a cross-sectional study.Frontiers in public health · 2026Article
- Clinical Application of Deep Learning for Spine MRI Interpretation: A Multicenter Evaluation of Artificial-Intelligence-Assisted versus Manual Reading on Diagnostic Agreement with the Reference Standard.Research (Washington, D.C.) · 2026Article
- Biomechanical compensatory chain and residual compensation potential in aging spinal deformity: a narrative review and multimodal assessment framework.Frontiers in medicine · 2026Review
- Relationships between hand grip strength and gait parameters measured using a foot-mounted sensor in non-laboratory settings in older women.Scientific reports · 2025Article
- Osteoporosis in adjacent cervical segments exacerbates disc herniation.Scientific reports · 2025Article
- Activities of daily living limitations in relation to the presence of pain in community-dwelling older adults.Scientific reports · 2025Article
- Age-threshold for increased risk of developing back disorders: prospective cohort with 74 000 individuals from the UK Biobank.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Improving Golf Swing Kinematics in a 78-Year-Old Golfer with Lower Back Pain: A Case Report.The American journal of case reports · 2024Article
- Hidden blood loss of minimally invasive transforaminal lumbar interbody fusion of lumbar degenerative diseases in patients with osteoporosis: a retrospective study.Journal of orthopaedic surgery and research · 2024Article
Corrections and comments
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Authors and funding
13 authors.
Funding
Abstract
Osteoporosis, vertebral fractures, and spinal degenerative diseases are common conditions that often coexist in older adults. This study aimed to determine the factors influencing low back pain and its impact on activities of daily living (ADL) and physical performance in older individuals with multiple comorbidities. This cross-sectional study was part of a large-scale population-based cohort study in Japan, involving 1009 participants who underwent spinal magnetic resonance imaging (MRI) to assess cervical cord compression, radiographic lumbar spinal stenosis, and lumbar disc degeneration. Vertebral fractures in the thoracolumbar spine were evaluated using sagittal MRI with a semi-quantitative method. Bone mineral density was measured using dual-energy X-ray absorptiometry. Low back pain, Oswestry Disability Index (ODI), and physical performance tests, such as one-leg standing time, five times chair-stand time, maximum walking speed, and maximum step length, were assessed. Using clinical conditions as objective variables and image evaluation parameters as explanatory variables, multiple regression analysis showed that vertebral fractures were significantly associated with low back pain and ODI. Vertebral fractures and osteoporosis significantly impacted physical performance, whereas osteoporosis alone did not affect low back pain or ODI. Our findings contribute to new insights into low back pain and its impact on ADL and physical performance.
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Registered trials
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