ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2024
Secretagogue-induced pancreatitis in mice devoid of chymotrypsin.
Article in American journal of physiology. Gastrointestinal and liver physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Reevaluating the role of TRPV6 deficiency in human and mouse pancreatitis.American journal of physiology. Gastrointestinal and liver physiology · 2026Article
- Integrative Genomics Reveals Causal Pleiotropy and Therapeutic Opportunities at the Interface of Acute Pancreatitis and Infection.Journal of hepato-biliary-pancreatic sciences · 2026Article
- Chymotrypsin Deficiency Accelerates Precancerous Remodeling of the Pancreas in KC Mice.Pancreas · 2026Article
- Strain-specific differences in cerulein-induced acute and recurrent acute murine pancreatitis.Scientific reports · 2025Article
- Engineering mouse chymotrypsin B1 for improved trypsinogen degradation.Scientific reports · 2025Article
- Pain - related methylation driver genes affect the prognosis of pancreatic cancer patients by altering immune function and perineural infiltration.Frontiers in genetics · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
The serine protease chymotrypsin protects the pancreas against pancreatitis by degrading trypsinogen, the precursor to the digestive protease trypsin. Taking advantage of previously generated mouse models with either the
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.