Evidence map›Paper›PMID 38981028›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

Blood Brain Barrier-Crossing Delivery of Felodipine Nanodrug Ameliorates Anxiety-Like Behavior and Cognitive Impairment in Alzheimer's Disease.

Xiaofei He, Yuan Peng, Sicong Huang, Zecong Xiao, Ge Li, Zejie Zuo, Liying Zhang, Xintao Shuai, Haiqing Zheng, Xiquan Hu

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xiaofei HeDepartment of Rehabilitation Medicine, The Third Affiliated Hospital, Sun Yat-sen University, 600 Tianhe Road, Guangzhou, Guangdong, 510630, China.
Yuan PengDepartment of Rehabilitation Medicine, Guangzhou First People's Hospital, Guangzhou, 510180, China.
Sicong HuangSchool of Materials Science and Engineering Sun Yat-sen University, Guangzhou, 510275, China.
Zecong XiaoNanomedicine Research Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, China.
Ge LiGuangdong Provincial Key Laboratory of Laboratory Animals, Guangdong Laboratory Animals Monitoring Institute, 11 Fengxin Road, Guangzhou, Guangdong, 510663, China.
Zejie ZuoDepartment of Rehabilitation Medicine, The Third Affiliated Hospital, Sun Yat-sen University, 600 Tianhe Road, Guangzhou, Guangdong, 510630, China.
Liying ZhangDepartment of Rehabilitation Medicine, The Third Affiliated Hospital, Sun Yat-sen University, 600 Tianhe Road, Guangzhou, Guangdong, 510630, China.
Xintao ShuaiNanomedicine Research Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, China.ORCID 0000-0003-4271-0310
Haiqing ZhengDepartment of Rehabilitation Medicine, The Third Affiliated Hospital, Sun Yat-sen University, 600 Tianhe Road, Guangzhou, Guangdong, 510630, China.
Xiquan HuDepartment of Rehabilitation Medicine, The Third Affiliated Hospital, Sun Yat-sen University, 600 Tianhe Road, Guangzhou, Guangdong, 510630, China.

Funding

National Key Research and Development Program of China 2022YFC3601200National Natural Science Foundation of China 51933011National Natural Science Foundation of China 82172546National Natural Science Foundation of China 82272609
6 · The paper itself

Abstract

Alzheimer's disease (AD) is the most common age-related neurodegenerative disorder leading to cognitive decline. Excessive cytosolic calcium (Ca

Indexed as

Alzheimer DiseaseBlood-Brain BarrierCognitive DysfunctionDisease Models, AnimalFelodipineAnimalsAnxietyBehavior, AnimalCalcium Channel BlockersDrug Delivery SystemsMiceCalcium Channel BlockersFelodipineAlzheimer's diseasecognitive impairmentER UPRmicrogliananoparticles

Identifiers

PMID38981028
PMCPMC11425895

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.