Evidence map›Paper›PMID 38981027›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

Automatic Clinical Assessment of Swallowing Behavior and Diagnosis of Silent Aspiration Using Wireless Multimodal Wearable Electronics.

Beomjune Shin, Sung Hoon Lee, Kangkyu Kwon, Yoon Jae Lee, Nikita Crispe, So-Young Ahn, Sandeep Shelly, Nathaniel Sundholm, Andrew Tkaczuk, Min-Kyung Yeo and 2 more

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Wearable bioelectronics for cancer theranostics.Microsystems & nanoengineering · 2025
    Review
  10. Article
  11. Article
  12. FromMaterials today. Bio · 2025
    Review
  13. Article
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Beomjune ShinGeorge W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA, 30332, USA.
Sung Hoon LeeWearable Intelligent Systems and Healthcare Center (WISH Center), Institute for Matter and Systems, Georgia Institute of Technology, Atlanta, GA, 30332, USA.
Kangkyu KwonWearable Intelligent Systems and Healthcare Center (WISH Center), Institute for Matter and Systems, Georgia Institute of Technology, Atlanta, GA, 30332, USA.
Yoon Jae LeeWearable Intelligent Systems and Healthcare Center (WISH Center), Institute for Matter and Systems, Georgia Institute of Technology, Atlanta, GA, 30332, USA.
Nikita CrispeWearable Intelligent Systems and Healthcare Center (WISH Center), Institute for Matter and Systems, Georgia Institute of Technology, Atlanta, GA, 30332, USA.
So-Young AhnDepartment of Rehabilitation Medicine, Chungnam National University School of Medicine, Daejeon, 35015, Republic of Korea.
Sandeep ShellyDepartment of Otolaryngology-Head and Neck Surgery, School of Medicine, Emory University, Atlanta, GA, 30322, USA.
Nathaniel SundholmDepartment of Otolaryngology-Head and Neck Surgery, School of Medicine, Emory University, Atlanta, GA, 30322, USA.
Andrew TkaczukDepartment of Otolaryngology-Head and Neck Surgery, School of Medicine, Emory University, Atlanta, GA, 30322, USA.
Min-Kyung YeoDepartment of Pathology, Chungnam National University School of Medicine, Daejeon, 35015, Republic of Korea.
Hyojung J ChooDepartment of Cell Biology, School of Medicine, Emory University, Atlanta, GA, 30322, USA.
Woon-Hong YeoGeorge W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA, 30332, USA.ORCID 0000-0002-5526-3882

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
Development of Nanomembrane Electronics and Machine-Learning Algorithms for Quantitative Screening of Dysphagia TherapeuticsR21EB031535 · NIBIB · GEORGIA INSTITUTE OF TECHNOLOGY · PI YEO, WOON-HONG · 2021 to 2023
$646k
Emory School of MedicineGeorgia Tech, and through the Georgia CTSA NIH UL1-TR002378Korea Health Industry Development Institute HR20C0025National Nanotechnology Coordinated InfrastructureNCATS NIH HHS UL1 TR002378NIBIB NIH HHS R21 EB031535NIH HHS R21EB031535NSF ECCS-2025462the WISH Center
6 · The paper itself

Abstract

Dysphagia is more common in conditions such as stroke, Parkinson's disease, and head and neck cancer. This can lead to pneumonia, choking, malnutrition, and dehydration. Currently, the diagnostic gold standard uses radiologic imaging, the videofluoroscopic swallow study (VFSS); however, it is expensive and necessitates specialized facilities and trained personnel. Although several devices attempt to address the limitations, none offer the clinical-grade quality and accuracy of the VFSS. Here, this study reports a wireless multimodal wearable system with machine learning for automatic, accurate clinical assessment of swallowing behavior and diagnosis of silent aspirations from dysphagia patients. The device includes a kirigami-structured electrode that suppresses changes in skin contact impedance caused by movements and a microphone with a gel layer that effectively blocks external noise for measuring high-quality electromyograms and swallowing sounds. The deep learning algorithm offers the classification of swallowing patterns while diagnosing silent aspirations, with an accuracy of 89.47%. The demonstration with post-stroke patients captures the system's significance in measuring multiple physiological signals in real-time for detecting swallowing disorders, validated by comparing them with the VFSS. The multimodal electronics can ensure a promising future for dysphagia healthcare and rehabilitation therapy, providing an accurate, non-invasive alternative for monitoring swallowing and aspiration events.

Indexed as

DeglutitionDeglutition DisordersWearable Electronic DevicesAgedElectromyographyFemaleHumansMaleWireless Technologydysphagiakirigami structuremachine learningsilent aspirationswallowing disorderwearable electronics

Identifiers

PMID38981027
PMCPMC11425633

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.