Evidence map›Paper›PMID 38980927›Full record

ArticleACS applied materials & interfaces2024

Upconverting Nanoparticle-based Enhanced Luminescence Lateral-Flow Assay for Urinary Biomarker Monitoring.

Marylyn Setsuko Arai, Hyunho Kim, Madeleine Pascavis, Baekdong Cha, Gabriel Brambilla, Young Kwan Cho, Jinho Park, Raquel R C Vilela, Andrea S S de Camargo, Cesar M Castro and 1 more

Abstract read
In one paragraph

Article in ACS applied materials & interfaces, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Marylyn Setsuko AraiSão Carlos Institute of Physics, University of São Paulo, São Carlos, SP 13566-590, Brazil.ORCID 0000-0003-1278-5274
Hyunho KimCenter for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, United States.ORCID 0000-0003-3072-6526
Madeleine PascavisCenter for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, United States.
Baekdong ChaKorea Institute of Machinery & Material, Daejeon 34103, South Korea.ORCID 0000-0003-0313-4998
Gabriel BrambillaSão Carlos Institute of Physics, University of São Paulo, São Carlos, SP 13566-590, Brazil.ORCID 0000-0003-1382-866X
Young Kwan ChoCenter for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, United States.ORCID 0000-0001-7516-5000
Jinho ParkCenter for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, United States.ORCID 0009-0003-9943-6903
Raquel R C VilelaSão Carlos Institute of Physics, University of São Paulo, São Carlos, SP 13566-590, Brazil.ORCID 0000-0001-7613-9461
Andrea S S de CamargoGlass Division, Federal Institute of Materials Research and Testing (BAM), 12489 Berlin ,Germany.ORCID 0000-0001-8352-2573
Cesar M CastroCenter for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, United States.ORCID 0000-0002-1159-5658
Hakho LeeCenter for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, United States.ORCID 0000-0002-0087-0909

Funding

Expanding early cancer detection with high throughput OCEANA - Ovarian Cancer Exosome Analysis with Nanoplasmonic ArrayU01CA284982 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI Cesar M Castro, Hakho Lee · 2023 to 2026
$3.7M
CaNCURE: Cancer Nanomedicine Co-ops For Undergraduate Research ExperiencesR25CA174650 · NCI · NORTHEASTERN UNIVERSITY · PI SRINIVAS SRIDHAR · 2014 to 2026
$3.4M
High throughput nanoplasmonic exosome testing (NEXT) of immunotherapies in bladder cancerR01CA264363 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI CASTRO, CESAR M, LEE, HAKHO · 2021 to 2024
$2.4M
Composing CODAs to cervical cancer screening through an integrated CRISPR and fluorescent nucleic acid approachU01CA279858 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI Cesar M Castro, Hakho Lee · 2023 to 2026
$2.1M
3D Fourier Imaging System for High Throughput Analyses of Cancer OrganoidsR21CA267222 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI LEE, HAKHO · 2022 to 2024
$613k
NCI NIH HHS R01 CA264363NCI NIH HHS R21 CA267222NCI NIH HHS R25 CA174650NCI NIH HHS U01 CA279858NCI NIH HHS U01 CA284982
6 · The paper itself

Abstract

Development of efficient portable sensors for accurately detecting biomarkers is crucial for early disease diagnosis, yet remains a significant challenge. To address this need, we introduce the enhanced luminescence lateral-flow assay, which leverages highly luminescent upconverting nanoparticles (UCNPs) alongside a portable reader and a smartphone app. The sensor's efficiency and versatility were shown for kidney health monitoring as a proof of concept. We engineered Er

Indexed as

BiomarkersGoldHepatitis A Virus Cellular Receptor 1Lipocalin-2NanoparticlesAcute Kidney InjuryBiosensing TechniquesErbiumHumansLimit of DetectionLuminescenceLuminescent MeasurementsSilicon DioxideThuliumBiomarkersErbiumGoldHAVCR1 protein, humanHepatitis A Virus Cellular Receptor 1LCN2 protein, humanLipocalin-2Silicon DioxideThuliumbiosensorkidney injurylateral flowportable sensorupconverting nanoparticles

Identifiers

PMID38980927
PMCPMC13236632

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.