Evidence map›Paper›PMID 38980902›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Lakshmi E Batachari, Alyssa Y Dai, Emily R Troemel

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Viral infection drives cell-intrinsic re-localization of thebioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. ThebioRxiv : the preprint server for biology · 2025
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Intraspecific variation in the duration of epigenetic inheritance.bioRxiv : the preprint server for biology · 2025
    Article
  16. Article
  17. Review
  18. Article
  19. Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  20. Article
4 · The record

Corrections and comments

  • Update of
    2024
5 · Who and what money

Authors and funding

3 authors.

Lakshmi E BatachariSchool of Biological Sciences, Department of Cell and Developmental Biology, University of California, San Diego, La Jolla, CA 92093.
Alyssa Y DaiSchool of Biological Sciences, Department of Cell and Developmental Biology, University of California, San Diego, La Jolla, CA 92093.
Emily R TroemelSchool of Biological Sciences, Department of Cell and Developmental Biology, University of California, San Diego, La Jolla, CA 92093.ORCID 0000-0003-2422-0473

Funding

The Intracellular Pathogen Response Triggers Defense Against Co-evolved PathogensR01GM114139 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Emily R Troemel · 2015 to 2026
$3.1M
Probing organismal proteostasis through the response to intracellular infectionR01AG052622 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Emily R Troemel · 2017 to 2026
$2.7M
Innate immunity against viral infection in intestinal epithelial cells of C. elegansR01AI176639 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Emily R Troemel · 2023 to 2026
$1.5M
Probing organismal proteostasis through the response to intracellular infectionR56AG052622 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI TROEMEL, EMILY R · 2016 to 2016
$388k
HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) AI176639HHS | NIH | National Institute of General Medical Sciences (NIGMS) GM114139National Institutes of Aging AG052622NIAID NIH HHS R01 AI176639NIA NIH HHS R01 AG052622NIA NIH HHS R56 AG052622NIGMS NIH HHS R01 GM114139NSF (NSF) 2301657
6 · The paper itself

Abstract

Upon sensing viral RNA, mammalian RIG-I-like receptors (RLRs) activate downstream signals using caspase activation and recruitment domains (CARDs), which ultimately promote transcriptional immune responses that have been well studied. In contrast, the downstream signaling mechanisms for invertebrate RLRs are much less clear. For example, the

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsSignal TransductionAnimalsDEAD-box RNA HelicasesImmunity, InnateIntestinal MucosaIntestinesRNA, Double-StrandedRNA, ViralCaenorhabditis elegans ProteinsDEAD-box RNA HelicasesDRH-1 protein, C elegansRNA, Double-StrandedRNA, ViralC. elegansinnate immunityintracellular pathogen responseRIG-I-like receptorviral infection

Identifiers

PMID38980902
PMCPMC11260149

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.