Evidence map›Paper›PMID 38980791›Full record

ArticleThe Permanente journal2024

Analyzing Potential Interactions Between Complementary and Alternative Therapies, Over-the-Counter, and Prescription Medications in the Older Population.

Ecler Ercole Jaqua, Jody Gonzalez, Khaled Bahjri, Shasta Erickson, Clarissa Garcia, Montinee Santhavachart, Van Nguyen, Wessam Labib, Rasha Abdrabou

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PubMed Full text at PMC Publisher
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Article in The Permanente journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Utilization of Complementary and Alternative Medicine Among Patients with Cancer: A Cross-Sectional Study.Inquiry : a journal of medical care organization, provision and financing
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ecler Ercole JaquaLoma Linda University School of Medicine, Family Medicine Department, Geriatric Medicine Division, Loma Linda, CA, USA.ORCID 0000-0001-6694-1485
Jody GonzalezLoma Linda University, School of Pharmacy, Loma Linda, CA, USA.
Khaled BahjriLoma Linda University, School of Pharmacy, Loma Linda, CA, USA.ORCID 0000-0002-4422-1687
Shasta EricksonLoma Linda University, School of Pharmacy, Loma Linda, CA, USA.
Clarissa GarciaLoma Linda University, School of Pharmacy, Loma Linda, CA, USA.
Montinee SanthavachartLoma Linda University, School of Pharmacy, Loma Linda, CA, USA.
Van NguyenLoma Linda University Medical Center-Murrieta, Family Medicine Department, Loma Linda, CA, USA.
Wessam LabibLoma Linda University School of Medicine, Family Medicine Department, Geriatric Medicine Division, Loma Linda, CA, USA.
Rasha AbdrabouLoma Linda University, School of Allied Health Professions, Loma Linda, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe escalating use of complementary and alternative medicine (CAM) raises concerns, particularly among geriatric patients taking multiple medications. Notably, the doubled chance of major drug interactions between prescription and over-the-counter (OTC) drugs in older adults underscores the need for further research. This study aimed to evaluate clinically significant CAM and prescription medication interactions in a geriatric clinic, emphasizing the growing importance of understanding CAM implications in health care.

methodsA 2-year cross-sectional study, approved by the Institutional Review Board, enrolled 420 participants aged 65 and older from a geriatric primary care clinic. Participants completed a survey, and pharmacy students conducted chart reviews to evaluate potential CAM products and prescription medication interactions.

resultsAmong the 420 participants-who were predominantly White females and who were taking supplements, OTC medications, or both-15.6% experienced potential drug interactions.

conclusionThis study highlighted the significant use of CAM and/or OTC medications, particularly among vulnerable older adults, revealing a concerning 15.6% rate of potential drug interactions. The findings emphasized the need for awareness among health care practitioners and standardized CAM surveys to enhance accuracy and patient safety.

Indexed as

Complementary TherapiesDrug InteractionsNonprescription DrugsPrescription DrugsAgedAged, 80 and overCross-Sectional StudiesDietary SupplementsFemaleHumansMaleSurveys and QuestionnairesNonprescription DrugsPrescription Drugscomplementary and alternative medicinedrugshealthcareinteractionsmedicationsover-the-counter

Identifiers

PMID38980791
PMCPMC11232911

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.