Evidence map›Paper›PMID 38980644›Full record

ArticleDrugs & aging2024

Use of Muscle Relaxants After Surgery in Traditional Medicare Part D Enrollees.

Tasce Bongiovanni, Siqi Gan, Emily Finlayson, Joseph S Ross, James D Harrison, John Boscardin, Michael A Steinman

Abstract read
In one paragraph

Article in Drugs & aging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tasce BongiovanniDepartment of Surgery, University of California San Francisco School of Medicine, 513 Parnassus Ave, HSW 1600, San Francisco, CA, 94143-0790, USA. tascesimon@yahoo.com.
Siqi GanUniversity of California San Francisco Pepper Center, San Francisco, CA, USA.
Emily FinlaysonDepartment of Surgery, University of California San Francisco School of Medicine, 513 Parnassus Ave, HSW 1600, San Francisco, CA, 94143-0790, USA.
Joseph S RossCenter for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, CT, USA.
James D HarrisonDivision of Hospital Medicine, University of California San Francisco School of Medicine, San Francisco, CA, USA.
John BoscardinDepartment of Medicine, University of California San Francisco School of Medicine, San Francisco, CA, USA.
Michael A SteinmanDivision of Geriatrics, University of California San Francisco School of Medicine, San Francisco, CA, USA.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Institutional Career Development Core SupplementKL2TR001870 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KANAYA, ALKA M., SARKAR, URMIMALA · 2016 to 2025
$19.7M
Understanding and Improving Surgical Decision-Making for Persons Living with Dementia, their Family Caregivers, and their Providers: A Mixed Methods StudyR01AG067507 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI WEISSMAN, JOEL S. · 2020 to 2024
$4.4M
Leveraging Physician Networks to Improve Care and Outcomes for Low-Income PopulationsR01HL144644 · NHLBI · YALE UNIVERSITY · PI NDUMELE, CHIMA · 2019 to 2021
$1.6M
Placing patient preferences at the center of care plans for older adults transitioning from the hospital to a skilled nursing facilityK01AG073533 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HARRISON, JAMES DAVID · 2021 to 2025
$660k
Prolonged Use of Pain Medication Past the Postoperative Period in Older AdultsK23AG073523 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BONGIOVANNI, TASCE RIIKA SIMON · 2022 to 2025
$653k
AHRQ HHS R01 HS025164FDA HHS U01 FD005938National Institute of Health (US) K24AG049057National Institute of Health (US) P30AG044281National Institute of Health (US) R01AG058616National Institute of Health (US) R01AG067507National Institute of Health (US) R24AG064025NCATS NIH HHS KL2 TR001870NCATS NIH HHS KL2TR001870NCATS NIH HHS UL1 TR001863NHLBI NIH HHS R01 HL144644NIA NIH HHS K01 AG073533NIA NIH HHS K01AG073533NIA NIH HHS K23AG073523NIA NIH HHS R01 AG067507Robert Wood Johnson Foundation P0553126
6 · The paper itself

Abstract

backgroundSurgeons have come under increased scrutiny for postoperative pain management, particularly for opioid prescribing. To decrease opioid use but still provide pain control, nonopioid medications such as muscle relaxants are being used, which can be harmful in older adults. However, the prevalence of muscle relaxant prescribing, trends in use over time, and risk of prolonged use are unknown. STUDY

designUsing a 20% representative Medicare sample, we conducted a retrospective analysis of muscle relaxant prescribing to patients ≥ 65 years of age. We merged patient data from Medicare Carrier, MedPAR, and Outpatient Files with Medicare Part D for the years 2013-2018. A total of 14 surgical procedures were included to represent a wide range of anatomic regions and specialties.

resultsThe study cohort included 543,929 patients. Of the cohort, 8111 (1.5%) received a new muscle relaxant prescription at discharge. Spine procedures accounted for 12% of all procedures but 56% of postoperative prescribing. Overall, the rate of prescribing increased over the time period (1.4-2.0%, p < 0.001), with increases in prescribing primarily in the spine (7-9.6%, p < 0.0001) and orthopedic procedure groups (0.9-1.4%, p < 0.0001). Of patients discharged with a new muscle relaxant prescription, 10.7% had prolonged use.

conclusionsThe use of muscle relaxants in the postoperative period for older adults is low, but increasing over time, especially in ortho and spine procedures. While pain control after surgery is crucial, surgeons should carefully consider the risks of muscle relaxant use, especially for older adults who are at higher risk for medication-related problems.

Indexed as

Medicare Part DPostoperative PainAgedAged, 80 and overDrug PrescriptionsFemaleHumansMalePractice Patterns, Physicians'Retrospective StudiesUnited States

Identifiers

PMID38980644
PMCPMC11249446

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.