Evidence map›Paper›PMID 38980631›Full record

ArticleGeroScience2024

Phylloquinone improves endothelial function, inhibits cellular senescence, and vascular inflammation.

Anna Kieronska-Rudek, Agnieszka Kij, Anna Bar, Anna Kurpinska, Tasnim Mohaissen, Marek Grosicki, Marta Stojak, Magdalena Sternak, Elżbieta Buczek, Bartosz Proniewski and 8 more

Abstract read
In one paragraph

Article in GeroScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Anna Kieronska-RudekJagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Krakow, Poland.ORCID 0000-0002-5447-0812
Agnieszka KijJagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Krakow, Poland.ORCID 0000-0003-2233-0564
Anna BarJagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Krakow, Poland.ORCID 0000-0003-0182-6501
Anna KurpinskaJagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Krakow, Poland.ORCID 0000-0003-2130-0099
Tasnim MohaissenJagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Krakow, Poland.ORCID 0000-0001-7495-3945
Marek GrosickiJagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Krakow, Poland.ORCID 0000-0002-0122-719X
Marta StojakJagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Krakow, Poland.ORCID 0000-0003-2291-4068
Magdalena SternakJagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Krakow, Poland.ORCID 0000-0001-9690-5231
Elżbieta BuczekJagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Krakow, Poland.ORCID 0000-0003-4955-3872
Bartosz ProniewskiJagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Krakow, Poland.ORCID 0000-0002-5138-1451
Kamil KuśJagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Krakow, Poland.ORCID 0000-0002-6959-5175
Joanna Suraj-PrazmowskaJagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Krakow, Poland.ORCID 0000-0002-0190-2474
Agnieszka PanekInstitute of Nuclear Physics Polish Academy of Sciences, Krakow, Poland.ORCID 0000-0002-3162-2668
Monika PietrowskaCentre for Translational Research and Molecular Biology of Cancer, Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice, Poland.ORCID 0000-0001-9317-7822
Szczepan ZapotocznyDepartment of Physical Chemistry and Electrochemistry, Faculty of Chemistry, Jagiellonian University, Krakow, Poland.ORCID 0000-0001-6662-7621
Catherine M ShanahanSchool of Cardiovascular and Metabolic Medicine and Sciences, James Black Centre, King's College London, London, UK.ORCID 0000-0002-8352-8171
Csaba SzaboChair of Pharmacology, Faculty of Science and Medicine, University of Fribourg, Fribourg, Switzerland.ORCID 0000-0003-3110-4235
Stefan ChlopickiJagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Krakow, Poland. stefan.chlopicki@jcet.eu.ORCID 0000-0002-2878-3858

Funding

Narodowe Centrum Badań i Rozwoju POWR.03.02.00-00-I013/16Narodowe Centrum Nauki 2018/29/B/NZ7/01684Narodowe Centrum Nauki 2018/31/N/NZ7/03900Schweizerischer Nationalfonds 310030L_204371
6 · The paper itself

Abstract

Phylloquinon (PK) and menaquinones (MK) are both naturally occurring compounds belonging to vitamin K group. Present study aimed to comprehensively analyze the influence of PK in several models of vascular dysfunction to determine whether PK has vasoprotective properties, similar to those previously described for MK. Effects of PK and MK on endothelial dysfunction were studied in ApoE/LDLR

Indexed as

Cellular SenescenceEndothelium, VascularVitamin K 1AnimalsAortaDisease Models, AnimalInflammationMaleMiceMice, Inbred C57BLMice, KnockoutVasodilationVitamin K 2Vitamin K 1Vitamin K 2Anti-inflammatoryAnti-senescenceDNA damageVasoprotectionVitamin K1Vitamin K2

Identifiers

PMID38980631
PMCPMC11336140

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.