ArticleNeuroradiology2024
Defining tumor growth in vestibular schwannomas: a volumetric inter-observer variability study in contrast-enhanced T1-weighted MRI.
Article in Neuroradiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Long-term Outcomes of Hypo- and Conventional Fractionated Stereotactic Radiotherapy for Non-vestibular Schwannomas: A Retrospective Cohort Study from Ramathibodi Hospital.Neurologia medico-chirurgica · 2026Article
- Pseudoprogression in Koos grade 4 vestibular schwannomas following stereotactic radiosurgery: temporal dynamics and radiological predictors.Journal of neuro-oncology · 2026Article
- Dynamic contrast-enhanced and diffusion-weighted MR imaging for predicting tumor growth of sporadic vestibular schwannomas: A prospective study.Neuro-oncology · 2025Article
- Towards clinical implementation of automated segmentation of vestibular schwannomas: a reliability study comparing AI and human performance.Neuroradiology · 2025Article
- Evaluating the effect of voxel size on the accuracy of 3D volumetric analysis measurements of brain tumors.Frontiers in radiology · 2025Article
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7 authors.
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Abstract
purposeFor patients with vestibular schwannomas (VS), a conservative observational approach is increasingly used. Therefore, the need for accurate and reliable volumetric tumor monitoring is important. Currently, a volumetric cutoff of 20% increase in tumor volume is widely used to define tumor growth in VS. The study investigates the tumor volume dependency on the limits of agreement (LoA) for volumetric measurements of VS by means of an inter-observer study.
methodsThis retrospective study included 100 VS patients who underwent contrast-enhanced T1-weighted MRI. Five observers volumetrically annotated the images. Observer agreement and reliability was measured using the LoA, estimated using the limits of agreement with the mean (LOAM) method, and the intraclass correlation coefficient (ICC).
resultsThe 100 patients had a median average tumor volume of 903 mm
conclusionAgreement limits within volumetric annotation of VS are affected by tumor volume, since the LoA improves with increasing tumor volume. As a result, for tumors larger than 200 mm
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