Evidence map›Paper›PMID 38980300›Full record

ArticleeLife2024

Comparative transcriptomics reveal a novel tardigrade-specific DNA-binding protein induced in response to ionizing radiation.

Marwan Anoud, Emmanuelle Delagoutte, Quentin Helleu, Alice Brion, Evelyne Duvernois-Berthet, Marie As, Xavier Marques, Khadija Lamribet, Catherine Senamaud-Beaufort, Laurent Jourdren and 15 more

Abstract readComparative Study
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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  16. Transcriptome analysis of the tardigrade Hypsibius exemplaris exposed to the DNA-damaging agent bleomycin.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Marwan Anoud *Département AVIV, MNHN, CNRS UMR7196, INSERM U1154, Paris, France.
Emmanuelle Delagoutte *Département AVIV, MNHN, CNRS UMR7196, INSERM U1154, Paris, France.
Quentin Helleu *Département AVIV, MNHN, CNRS UMR7196, INSERM U1154, Paris, France.
Alice BrionDépartement AVIV, MNHN, CNRS UMR7196, INSERM U1154, Paris, France.
Evelyne Duvernois-BerthetDépartement AVIV, MNHN, CNRS UMR7221, Paris, France.ORCID https://orcid.org/0000-0003-1442-6603
Marie AsDépartement AVIV, MNHN, CNRS UMR7196, INSERM U1154, Paris, France.
Xavier MarquesDépartement AVIV, MNHN, CNRS UMR7196, INSERM U1154, Paris, France.
Khadija LamribetDépartement AVIV, MNHN, CNRS UMR7196, INSERM U1154, Paris, France.
Catherine Senamaud-BeaufortGénomique ENS, Institut de Biologie de l'ENS (IBENS), Ecole Normale Supérieure, CNRS, INSERM, Université PSL, Paris, France.ORCID https://orcid.org/0000-0001-7074-0416
Laurent JourdrenGénomique ENS, Institut de Biologie de l'ENS (IBENS), Ecole Normale Supérieure, CNRS, INSERM, Université PSL, Paris, France.ORCID https://orcid.org/0000-0003-4253-1048
Annie AdraitUniv. Grenoble Alpes, INSERM, CEA, UA13 BGE, CNRS, CEA, Grenoble, France.
Sophie HeinrichInstitut Curie, Inserm U1021-CNRS UMR 3347, Université Paris-Saclay, Université PSL, Orsay Cedex, France.
Geraldine ToutiraisPlateforme technique de Microscopie Electronique, MNHN, Paris, France.
Sahima HamlaouiDépartement AVIV MNHN, UMR7245, Paris, France.
Giacomo GroppleroMMBM, Institut Curie, CNRS UMR168, Paris, France.
Ilaria GiovanniniDepartment of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Loic PongerDépartement AVIV, MNHN, CNRS UMR7196, INSERM U1154, Paris, France.
Marc GezeCeMIM, MNHN, CNRS UMR7245, Paris, France.
Corinne BlugeonGénomique ENS, Institut de Biologie de l'ENS (IBENS), Ecole Normale Supérieure, CNRS, INSERM, Université PSL, Paris, France.ORCID https://orcid.org/0000-0001-5820-8785
Yohann CoutéUniv. Grenoble Alpes, INSERM, CEA, UA13 BGE, CNRS, CEA, Grenoble, France.ORCID https://orcid.org/0000-0003-3896-6196
Roberto GuidettiDepartment of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.ORCID https://orcid.org/0000-0001-6079-2538
Lorena RebecchiDepartment of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Carine GiovannangeliDépartement AVIV, MNHN, CNRS UMR7196, INSERM U1154, Paris, France.
Anne De CianDépartement AVIV, MNHN, CNRS UMR7196, INSERM U1154, Paris, France.ORCID https://orcid.org/0000-0002-1737-2543
Jean-Paul ConcordetDépartement AVIV, MNHN, CNRS UMR7196, INSERM U1154, Paris, France.ORCID https://orcid.org/0000-0001-8924-4316

Funding

Agence Nationale de la Recherche ANR-10-INBS-0008Agence Nationale de la Recherche ANR-10-INBS-0009Agence Nationale de la Recherche ANR-17-EURE-0003Agence Nationale de la Recherche ANR-II-INBS-0014Sorbonne Université SU-19-3-EMRG-06
6 · The paper itself

Abstract

Tardigrades are microscopic animals renowned for their ability to withstand extreme conditions, including high doses of ionizing radiation (IR). To better understand their radio-resistance, we first characterized induction and repair of DNA double- and single-strand breaks after exposure to IR in the model species

Indexed as

DNA-Binding ProteinsDNA RepairRadiation, IonizingTardigradaTranscriptomeAnimalsDNA DamageGene Expression ProfilingHumansRadiation ToleranceDNA-Binding ProteinschromosomesDNA repairgene expressionionizing radiationtardigrade

Identifiers

PMID38980300
PMCPMC11233135

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.