Evidence map›Paper›PMID 38980154›Full record

ReviewThe Plant cell2024

The lowdown on breakdown: Open questions in plant proteolysis.

Nancy A Eckardt, Tamar Avin-Wittenberg, Diane C Bassham, Poyu Chen, Qian Chen, Jun Fang, Pascal Genschik, Abi S Ghifari, Angelica M Guercio, Daniel J Gibbs and 21 more

Abstract readReview
In one paragraph

Review in The Plant cell, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. The Involvement of thePlants (Basel, Switzerland) · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Focus on proteolysis.The Plant cell · 2024
    Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors.

Nancy A EckardtThe Plant Cell, American Society of Plant Biologists, USA.ORCID 0000-0003-1658-1412
Tamar Avin-WittenbergDepartment of Plant and Environmental Sciences, Alexander Silberman Institute of Life Sciences, Hebrew University of Jerusalem, Jerusalem 9190401, Israel.ORCID 0000-0002-3165-175X
Diane C BasshamDepartment of Genetics, Development and Cell Biology, Iowa State University, Ames, IA 50011, USA.ORCID 0000-0001-7411-9360
Poyu ChenSchool of Biological Science and Technology, College of Science and Engineering, Kanazawa University, Kakuma-machi, Kanazawa 920-1192, Japan.
Qian ChenMinistry of Agriculture and Rural Affairs Key Laboratory for Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University, Beijing 100193, China.ORCID 0000-0002-7916-1370
Jun FangSection of Molecular Plant Biology, Department of Biology, University of Oxford, Oxford OX1 3RB, UK.ORCID 0000-0003-2049-3271
Pascal GenschikInstitut de Biologie Moléculaire des Plantes, CNRS, Université de Strasbourg, 12, rue du Général Zimmer, Strasbourg 67084, France.ORCID 0000-0002-4107-5071
Abi S GhifariSchool of Molecular Sciences, The University of Western Australia, Crawley, Western Australia 6009, Australia.ORCID 0000-0003-2394-0102
Angelica M GuercioDepartment of Plant Biology, College of Biological Sciences, University of California-Davis, Davis, CA 95616, USA.ORCID 0000-0002-5464-1108
Daniel J GibbsSchool of Biosciences, University of Birmingham, Edgbaston B1 2RU, UK.ORCID 0000-0002-4100-6682
Maren HeeseDepartment of Developmental Biology, University of Hamburg, Ohnhorststr. 18, Hamburg 22609, Germany.ORCID 0000-0002-1070-9107
R Paul JarvisSection of Molecular Plant Biology, Department of Biology, University of Oxford, Oxford OX1 3RB, UK.ORCID 0000-0003-2127-5671
Simon MichaeliDepartment of Postharvest Sciences, Agricultural Research Organization (ARO), Volcani Institute, Rishon LeZion 7505101, Israel.ORCID 0000-0003-0123-6544
Monika W MurchaSchool of Molecular Sciences, The University of Western Australia, Crawley, Western Australia 6009, Australia.ORCID 0000-0002-3689-6158
Sergey MursalimovDepartment of Postharvest Sciences, Agricultural Research Organization (ARO), Volcani Institute, Rishon LeZion 7505101, Israel.ORCID 0000-0001-6935-4331
Sandra NoirInstitut de Biologie Moléculaire des Plantes, CNRS, Université de Strasbourg, 12, rue du Général Zimmer, Strasbourg 67084, France.ORCID 0000-0002-5666-2885
Malathy PalayamDepartment of Plant Biology, College of Biological Sciences, University of California-Davis, Davis, CA 95616, USA.ORCID 0000-0001-7031-947X
Bruno PeixotoSection of Molecular Plant Biology, Department of Biology, University of Oxford, Oxford OX1 3RB, UK.ORCID 0000-0002-1022-3908
Pedro L RodriguezInstituto de Biología Molecular y Celular de Plantas (IBMCP), Consejo Superior de Investigaciones Cientificas-Universidad Politecnica de Valencia, Valencia ES-46022, Spain.ORCID 0000-0002-5886-9425
Andreas SchallerDepartment of Plant Physiology and Biochemistry, Institute of Biology, University of Hohenheim, Stuttgart 70599, Germany.ORCID 0000-0001-6872-9576
Arp SchnittgerDepartment of Developmental Biology, University of Hamburg, Ohnhorststr. 18, Hamburg 22609, Germany.ORCID 0000-0001-7067-0091
Giovanna SerinoDepartment of Biology and Biotechnology, Sapienza Universita' di Roma, p.le A. Moro 5, Rome 00185, Italy.ORCID 0000-0001-8689-6132
Nitzan ShabekDepartment of Plant Biology, College of Biological Sciences, University of California-Davis, Davis, CA 95616, USA.ORCID 0000-0002-2190-5955
Annick StintziDepartment of Plant Physiology and Biochemistry, Institute of Biology, University of Hohenheim, Stuttgart 70599, Germany.ORCID 0000-0002-6479-8184
Frederica L TheodoulouPlant Sciences and the Bioeconomy, Rothamsted Research, Harpenden AL5 2JQ, UK.ORCID 0000-0002-8306-0716
Suayib ÜstünFaculty of Biology and Biotechnology, Ruhr-University of Bochum, Bochum 44780, Germany.ORCID 0000-0002-8049-296X
Klaas J van WijkSection of Plant Biology, School of Integrative Plant Sciences (SIPS), Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0001-9536-0487
Ning WeiSchool of Life Sciences, Southwest University, Chongqing 400715, China.ORCID 0000-0001-8827-1320
Qi XieState Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, the Innovative Academy of Seed Design, Chinese Academy of Sciences, Beijing 100101, China.ORCID 0000-0002-8262-9093
Feifei YuCollege of Grassland Science and Technology, China Agricultural University, Beijing 100083, China.ORCID 0000-0003-1984-2462
Hongtao ZhangPlant Sciences and the Bioeconomy, Rothamsted Research, Harpenden AL5 2JQ, UK.ORCID 0000-0002-4903-571X

Funding

Agence Nationale de la Recherche ANR-19-CE13-0032Biotechnology and Biological Sciences Research Council BB/V008587/1Green Engineering Institute Strategic Programme Grant BB/X010988/1IdEx Unistra ANR-10-IDEX-0002Israeli Ministry of Agriculture and Rural Development #12-16-0016Israeli Ministry of Science and Technology #0005816Israel Science Foundation #1942/19Italian Ministry of Education and Merit 2022T2737YNational Key R&D Program of China 2021YFD1201603-5National Natural Science Foundation of China 32250710144P.L. Rodriguez PID2020-113100RBThe National Science Foundation #2047396UK Research and Innovation Biotechnology and Biological Sciences Research Council BB/V007300/1U.S. Department of Energy DE-SC0023158.11US-Israel Binational Agricultural Research & Development IS-5553-22US National Science Foundation
6 · The paper itself

Abstract

Proteolysis, including post-translational proteolytic processing as well as protein degradation and amino acid recycling, is an essential component of the growth and development of living organisms. In this article, experts in plant proteolysis pose and discuss compelling open questions in their areas of research. Topics covered include the role of proteolysis in the cell cycle, DNA damage response, mitochondrial function, the generation of N-terminal signals (degrons) that mark many proteins for degradation (N-terminal acetylation, the Arg/N-degron pathway, and the chloroplast N-degron pathway), developmental and metabolic signaling (photomorphogenesis, abscisic acid and strigolactone signaling, sugar metabolism, and postharvest regulation), plant responses to environmental signals (endoplasmic-reticulum-associated degradation, chloroplast-associated degradation, drought tolerance, and the growth-defense trade-off), and the functional diversification of peptidases. We hope these thought-provoking discussions help to stimulate further research.

Indexed as

Plant ProteinsPlantsProteolysisProtein Processing, Post-TranslationalSignal TransductionPlant Proteins

Identifiers

PMID38980154
PMCPMC11371169

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.