Evidence map›Paper›PMID 38980083›Full record

ArticleJournal of bacteriology2024

Transcriptional and post-transcriptional mechanisms modulate cyclopropane fatty acid synthase through small RNAs in

Colleen M Bianco, Nancy N Caballero-Rothar, Xiangqian Ma, Kristen R Farley, Carin K Vanderpool

Abstract read
In one paragraph

Article in Journal of bacteriology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Colleen M BiancoDepartment of Microbiology, University of Illinois, Urbana, Illinois, USA.
Nancy N Caballero-RotharDepartment of Microbiology, University of Illinois, Urbana, Illinois, USA.ORCID 0009-0005-8592-541X
Xiangqian MaDepartment of Microbiology, University of Illinois, Urbana, Illinois, USA.
Kristen R FarleyDepartment of Microbiology, University of Illinois, Urbana, Illinois, USA.ORCID 0000-0002-0677-7895
Carin K VanderpoolDepartment of Microbiology, University of Illinois, Urbana, Illinois, USA.ORCID 0000-0002-2850-5532

Funding

Small RNA Regulation in BacteriaR35GM139557 · NIGMS · UNIVERSITY OF MINNESOTA · PI Carin K Vanderpool · 2021 to 2026
$2.6M
NIGMS NIH HHS R35 GM139557
6 · The paper itself

Abstract

The small RNA (sRNA) RydC strongly activates IMPORTANCE: Bacteria experience many environmental stresses that challenge their membrane integrity. To withstand these challenges, bacteria sense what stress is occurring and mount a response that protects membranes. Previous work documented the important roles of small RNA (sRNA) regulators in membrane stress responses. One sRNA, RydC, helps cells cope with membrane-disrupting stresses by promoting changes in the types of lipids incorporated into membranes. In this study, we identified a regulator, YieP, that controls when RydC is produced and additional sRNA regulators that modulate YieP levels and RydC activity. These findings illuminate a complex regulatory network that helps bacteria sense and respond to membrane stress.

Indexed as

Escherichia coliEscherichia coli ProteinsGene Expression Regulation, BacterialRNA, BacterialCyclopropanesDNA-Binding ProteinsFatty AcidsFatty Acid SynthasesMethyltransferasesRNA, Small UntranslatedTranscription FactorsTranscription, Geneticcyclopropane fatty acidsCyclopropanescyclopropane synthetaseDNA-Binding ProteinsEscherichia coli ProteinsFatty AcidsFatty Acid SynthasesGntR protein, E coliMethyltransferasesRNA, BacterialRNA, Small UntranslatedTranscription FactorsFNRHfqOmpRosmotic stressRNA sponge

Identifiers

PMID38980083
PMCPMC11340327

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.