Evidence map›Paper›PMID 38980036›Full record

ArticlemBio2024

MoRgs3 functions in intracellular reactive oxygen species perception-integrated cAMP signaling to promote appressorium formation in

Ruiming Zhang, Xinyu Liu, Jiayun Xu, Chen Chen, Zhaoxuan Tang, Chengtong Wu, Xinyue Li, Lei Su, Muxing Liu, Leiyun Yang and 4 more

Abstract read
In one paragraph

Article in mBio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ruiming ZhangDepartment of Plant Pathology, College of Plant Protection, Nanjing Agricultural University, Nanjing, China.
Xinyu Liu *Department of Plant Pathology, College of Plant Protection, Nanjing Agricultural University, Nanjing, China.ORCID 0000-0001-5793-6588
Jiayun XuDepartment of Plant Pathology, College of Plant Protection, Nanjing Agricultural University, Nanjing, China.
Chen ChenDepartment of Plant Pathology, College of Plant Protection, Nanjing Agricultural University, Nanjing, China.
Zhaoxuan TangDepartment of Plant Pathology, College of Plant Protection, Nanjing Agricultural University, Nanjing, China.
Chengtong WuDepartment of Plant Pathology, College of Plant Protection, Nanjing Agricultural University, Nanjing, China.
Xinyue LiDepartment of Plant Pathology, College of Plant Protection, Nanjing Agricultural University, Nanjing, China.
Lei SuDepartment of Plant Pathology, College of Plant Protection, Nanjing Agricultural University, Nanjing, China.
Muxing LiuDepartment of Plant Pathology, College of Plant Protection, Nanjing Agricultural University, Nanjing, China.
Leiyun YangDepartment of Plant Pathology, College of Plant Protection, Nanjing Agricultural University, Nanjing, China.
Gang LiDepartment of Plant Pathology, College of Plant Protection, Nanjing Agricultural University, Nanjing, China.
Haifeng ZhangDepartment of Plant Pathology, College of Plant Protection, Nanjing Agricultural University, Nanjing, China.ORCID 0000-0002-7963-9071
Ping WangDepartment of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA.ORCID 0000-0002-3851-2779
Zhengguang Zhang *Department of Plant Pathology, College of Plant Protection, Nanjing Agricultural University, Nanjing, China.ORCID 0000-0001-8253-4505

Funding

Towards a genome-wide CRISPR/Cas9 mutant library in Rhizopus delemarR21AI168867 · NIAID · LSU HEALTH SCIENCES CENTER · PI WANG, PING · 2022 to 2023
$404k
Isolation of mononuclear propagules from coenocytic hyphae of the mucormycosis pathogen Rhizopus delemarR03AI156254 · NIAID · LSU HEALTH SCIENCES CENTER · PI WANG, PING · 2021 to 2022
$147k
HHS | National Institutes of Health (NIH) AI156254, AI168867MOST | National Key Research and Development Program of China (NKPs) No. 2022YFD1700200MOST | National Natural Science Foundation of China (NSFC) 32293245NIAID NIH HHS R03 AI156254NIAID NIH HHS R21 AI168867Revitalization Foundation of Seed Industry of Jiangsu No. JBGS (2021)005Young Elite Scientists Sponsorship Program by CAST 2022QNRC001
6 · The paper itself

Abstract

Regulator of G-protein signaling (RGS) proteins exhibit GTPase-accelerating protein activities to govern G-protein function. In the rice blast fungus IMPORTANCE: We report that MoRgs3 becomes phosphorylated in an oxidative intracellular environment during the appressorium formation stage. We found that this phosphorylation is carried out by MoNdk1, a nucleoside diphosphate kinase. In addition, this phosphorylation leads to a higher binding affinity between MoRgs3 and MoCrn1, a coronin-like actin-binding protein that was implicated in the endocytic transport of several other RGS proteins of

Indexed as

Cyclic AMPFungal ProteinsPlant DiseasesReactive Oxygen SpeciesSignal TransductionAscomycotaGene Expression Regulation, FungalNucleoside-Diphosphate KinaseOryzaPhosphorylationRGS ProteinsVirulenceCyclic AMPFungal ProteinsNucleoside-Diphosphate KinaseReactive Oxygen SpeciesRGS Proteinspathogenicityprotein phosphorylationRGS signalingROS sensingthe blast fungus

Identifiers

PMID38980036
PMCPMC11323498

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.