Evidence map›Paper›PMID 38979824›Full record

ArticleJournal of the American Heart Association2024

Addition of Social Determinants of Health to Coronary Heart Disease Risk Prediction: The Multi-Ethnic Study of Atherosclerosis.

Brittany Saldivar Murphy, Yunbi Nam, Robyn L McClelland, Isaac Acquah, Miguel Cainzos-Achirica, Khurram Nasir, Wendy S Post, Melinda C Aldrich, Andrew P DeFilippis

Abstract readMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Brittany Saldivar MurphyDepartment of Medicine Vanderbilt University Medical Center Nashville TN USA.ORCID 0000-0002-2225-3442
Yunbi NamDepartment of Biostatistics University of Washington Seattle WA USA.ORCID 0000-0003-0777-3789
Robyn L McClellandDepartment of Biostatistics University of Washington Seattle WA USA.ORCID 0000-0002-2433-1512
Isaac AcquahDepartment of Medicine MedStar Union Memorial Hospital Baltimore MD USA.ORCID 0000-0003-2554-7806
Miguel Cainzos-AchiricaDepartment of Cardiology Parc de Salut Mar/IMIM Barcelona Spain.ORCID 0000-0002-8073-2337
Khurram NasirDivision of Cardiovascular Prevention and Wellness, Department of Cardiology Houston Methodist DeBakey Heart & Vascular Center Houston TX USA.ORCID 0000-0001-5376-2269
Wendy S PostDivision of Cardiology, Department of Medicine Johns Hopkins University Baltimore MD USA.ORCID 0000-0002-8655-5204
Melinda C AldrichDepartment of Medicine Vanderbilt University Medical Center Nashville TN USA.ORCID 0000-0003-3833-8448
Andrew P DeFilippisDivision of Cardiovascular Medicine Vanderbilt University Medical Center Nashville TN USA.ORCID 0000-0002-5135-9748

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSocial determinants of health (SDoH) are associated with cardiovascular risk factors and outcomes; however, they are absent from risk prediction models. We aimed to assess if the addition of SDoH improves the predictive ability of the MESA (Multi-Ethnic Study of Atherosclerosis) Risk Score. METHODS AND

resultsThis was a community-based prospective population cohort study that enrolled 6286 men and women, ages 45-84 years, who were free of clinical coronary heart disease (CHD) at baseline. Data from 10-year follow-up were examined for CHD events, defined as myocardial infarction, fatal CHD, resuscitated cardiac arrest, and revascularization in cases of anginal symptoms. Participants included 53% women with average age of 62 years. When adjusting for traditional cardiovascular risk factors, SDoH, and coronary artery calcium, economic strain, specifically low family income, was associated with a greater risk of CHD events (hazard ratio [HR], 1.42 [95% CI, 1.17-1.71],

conclusionsSignificant associations were found between economic/financial SDoH and CHD risk factors and outcomes. Incorporation of SDoH into the MESA Risk Score did not improve predictive ability of the model. Our findings do not support the incorporation of SDoH into current risk prediction algorithms.

Indexed as

Coronary DiseaseSocial Determinants of HealthAgedAged, 80 and overEthnicityFemaleHeart Disease Risk FactorsHumansMaleMiddle AgedPredictive Value of TestsPrognosisProspective StudiesRisk AssessmentRisk FactorsUnited Statescoronary diseaserisksocial determinants

Identifiers

PMID38979824
PMCPMC11292754

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.